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Developmental approach towards high resolution optical coherence tomography for glaucoma diagnostics

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  • Björn Kemper
  • Steffi Ketelhut
  • Peter Heiduschka
  • Marie Thorn
  • Michael Larsen
  • Jürgen Schnekenburger
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Glaucoma is caused by a pathological rise in the intraocular pressure, which results in a progressive loss of vision by a damage to retinal cells and the optical nerve head. Early detection of pressure-induced damage is thus essential for the reduction of eye pressure and to prevent severe incapacity or blindness. Within the new European Project GALAHAD (Glaucoma Advanced, Label free High Resolution Automated OCT Diagnostics), we will develop a new low-cost and high-resolution OCT system for the early detection of glaucoma. The device is designed to improve diagnosis based on a new system of optical coherence tomography. Although OCT systems are at present available in ophthalmology centres, high-resolution devices are extremely expensive. The novelty of the new Galahad system is its super wideband light source to achieve high image resolution at a reasonable cost. Proof of concept experiments with cell and tissue Glaucoma test standards and animal models are planned for the test of the new optical components and new algorithms performance for the identification of Glaucoma associated cell and tissue structures. The intense training of the software systems with various samples should result in a increased sensitivity and specificity of the OCT software system.

Original languageEnglish
Title of host publicationOphthalmic Technologies XXVIII
EditorsArthur Ho, Per G. Soderberg, Fabrice Manns
Publication date1 Jan 2018
Article number104742G
ISBN (Electronic)9781510614338
Publication statusPublished - 1 Jan 2018
Event28th Conference on Ophthalmic Technologies - San Francisco, United States
Duration: 27 Jan 201828 Jan 2018


Conference28th Conference on Ophthalmic Technologies
LandUnited States
BySan Francisco
SponsorThe Society of Photo-Optical Instrumentation Engineers (SPIE)
SeriesProgress in Biomedical Optics and Imaging - Proceedings of SPIE


28th Conference on Ophthalmic Technologies


San Francisco, United States

Event: Conference

    Research areas

  • Glaucoma, Glaucoma cell and tissue standards, image analysis algorithms, Optical Coherence Tomography

ID: 59452011