Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Development of a model to assess the cost-effectiveness of gestational diabetes mellitus screening and lifestyle change for the prevention of type 2 diabetes mellitus

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Characteristics, management and outcomes of very preterm triplets in 19 European regions

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. FIGO classification for the clinical diagnosis of placenta accreta spectrum disorders

    Research output: Contribution to journalReviewResearchpeer-review

  3. Cancer of the corpus uteri

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Self-perceived long-term transfer of learning after postpartum hemorrhage simulation training

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. FIGO consensus guidelines on placenta accreta spectrum disorders: Introduction

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Regional variation in out-of-hospital cardiac arrest: incidence and survival - a nationwide study of regions in Denmark

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. The clinical use of hyperbaric oxygen in the treatment of Danish patients with diabetic foot ulcers

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Short-stay unit hospitalisation vs. standard care outcomes in older internal medicine patients-a randomised clinical trial

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Anaesthesia practice in Denmark for relocation of the dislocated hip after total hip arthroplasty

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Characteristics of children aged 2-17 years undergoing anaesthesia in Danish hospitals 2005-2015: a national observational study

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

Gestational diabetes mellitus (GDM) is increasingly recognized as an opportunity for early prevention of diabetes and other diseases over the lifespan, and may be responsible for up to 30% of cases of type 2 diabetes. A newly developed mathematical model (the GDModel) provides provisional estimates of the cost and health impact of various GDM screening and management choices, and calculates averted disability-adjusted life-years (DALYs). The model was piloted in 5 different healthcare facilities in India and Israel. Universal screening of pregnant women followed by postpartum lifestyle management yielded net savings of US$78 per woman with GDM in India and US$1945 per woman in Israel. The estimated DALYs averted were 2.33 in India and 3.10 in Israel. With lower GDM prevalence, intervention efficacy, and type 2 diabetes incidence, the intervention had a net cost in India, with a cost per DALY averted of US$11.32. This was far below the WHO definition of "very cost-effective," set at annual GDP per capita. The intervention in Israel remained cost-saving. GDM screening and postpartum lifestyle management are either cost-saving or have a net cost but an attractive cost-effectiveness ratio. Some input values are currently being refined. Nevertheless, the current findings of cost-savings or favorable cost-effectiveness are robust to a wide range of plausible input values, including highly unfavorable values. The GDModel will be further developed into a user-friendly tool that can guide policy-makers on decisions regarding GDM screening strategies and guidelines.

Original languageEnglish
JournalInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Volume115 Suppl 1
Pages (from-to)S20-5
ISSN0020-7292
DOIs
Publication statusPublished - Nov 2011

    Research areas

  • Cost-Benefit Analysis, Diabetes Mellitus, Type 2/epidemiology, Diabetes, Gestational/diagnosis, Female, Health Policy/economics, Humans, Incidence, India/epidemiology, Israel/epidemiology, Mass Screening/economics, Models, Biological, Pregnancy, Pregnancy Complications/economics, Prenatal Exposure Delayed Effects/economics, Prevalence, Quality-Adjusted Life Years, Risk Reduction Behavior

ID: 54968376