Determination of the tissue-to-blood partition coefficient for 131iodo-antipyrine in human subcutaneous adipose tissue

R Jelnes, A Astrup

2 Citations (Scopus)

Abstract

131Iodo-antipyrine (131I-AP) is commonly used for blood flow measurements in adipose tissue. These estimations have been based on the assumption of the tissue-to-blood partition coefficient being 1 ml g-1. No exact determination of the tissue-to-blood partition coefficient for 131I-AP in adipose tissue has been carried out. In the present study a partition coefficient of 1.12 +/- 0.06 (mean +/- S.D.) for 131I-AP in adipose tissue has been determined based on the partition coefficient for 131I-AP between lipid-saline (1.24 ml g-1), red blood cells-plasma (0.64 ml g-1), protein-saline (0.19 ml g-1) and plasma-saline (0.84 ml ml-1).

Original languageEnglish
JournalScandinavian Journal of Clinical & Laboratory Investigation
Volume45
Issue number6
Pages (from-to)521-4
Number of pages4
ISSN0036-5513
Publication statusPublished - Oct 1985

Keywords

  • Adipose Tissue
  • Antipyrine
  • Humans

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