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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Determination of peripapillary vessel density in optic disc drusen using EDI-OCT and OCT angiography

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Optical coherence tomography angiography (OCTA) is a rapidly developing technique which generates angiographic images non-invasively. This study proposes a method to determine the vessel density in OCTA scans in general and especially the local peripapillary vessel density. The method produces vessel density heatmaps that contain information about the local vessel density. We apply the method in a small study to demonstrate its applicability and its potential to investigate the influence of local conditions on the vessel density. In the study, we combine information from enhanced depth imaging optical coherence tomography (EDI-OCT) about the location of optic disc drusen (ODD) with information from OCTA about the vessel density. We see a reduction in local peripapillary vessel density in peripapillary sections with a large volume of ODD.

Original languageEnglish
JournalExperimental Eye Research
Volume197
Pages (from-to)108123
ISSN0014-4835
DOIs
Publication statusPublished - Aug 2020

    Research areas

  • Female, Fluorescein Angiography/methods, Fundus Oculi, Humans, Male, Microvessels/pathology, Nerve Fibers/pathology, Optic Disk/blood supply, Optic Disk Drusen, Retinal Vessels/pathology, Tomography, Optical Coherence/methods, Visual Acuity, Visual Fields

ID: 61986508