Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Determinants of Neurodevelopment in Early Childhood - Results from the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC2010 ) Mother-Child Cohort

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Nationwide study found higher paediatric readiness in emergency departments and trauma centres with a paediatrician on-site

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. The mortality of immature infants, who decides?

    Research output: Contribution to journalEditorialResearchpeer-review

  3. Authors' reply regarding "On diagnosing and treating PANS/ PANDAS: questions from a patient support group"

    Research output: Contribution to journalLetterResearchpeer-review

  4. Brain tumours in children and adolescents may affect the circadian rhythm and quality of life

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Allergic comorbidity is a risk factor for not attending scheduled outpatient visits in children with asthma

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Long-term air pollution and road traffic noise exposure and COPD: the Danish Nurse Cohort

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Maternal 17q21 genotype influences prenatal vitamin D effects on offspring asthma/recurrent wheeze

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

Aim: The objective of this study was to identify possible pre- and postnatal factors influencing neurodevelopment of the young child. Methods: We used data from the Copenhagen Prospective Studies on Asthma in Childhood 2010 (COPSAC 2010) mother–child cohort, but excluded those with a neurological diagnosis, born <37 weeks of gestation and birthweights <2500 g, resulting in 650 children analysed. Neurodevelopment was assessed as age of achievement of early milestones, language scores at 1 and 2 years and cognitive score at 2 ½ years of age. Results: Neurodevelopmental scores were not associated with breastfeeding, persistent wheeze, eczema and number of sick days (p > 0.05 in all tests). Early age at milestone achievement was associated with male sex (p = 0.05), lower maternal age (p = 0.02), higher gestational age (p < 0.001) and paternity leave (p = 0.01). A higher 1-year language score was associated with female sex (p = 0.02) and maternal smoking during pregnancy (p = 0.01) and a higher 2-year language score with female sex (p < 0.001) and being first born (p = 0.01). A higher cognitive score was associated with female sex (p = 0.02). Conclusion: Neurodevelopmental scores were unrelated to breastfeeding, persistent wheeze, eczema and number of sick days. Neurodevelopment in early childhood was mostly associated with gender.

Original languageEnglish
JournalActa paediatrica
Volume108
Issue number9
Pages (from-to)1632-1641
Number of pages10
ISSN1651-2227
DOIs
Publication statusPublished - Sep 2019

Bibliographical note

©2019 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

    Research areas

  • Cognitive development, Language development, Motor development, Neurological development

ID: 56581669