Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Detecting autologous blood transfusions: a comparison of three passport approaches and four blood markers

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Response to Letter-to-Editor by Lixandrão et al. published in Scand. J. Med. Sci. Sports 31(2), 489-492, 2021

    Research output: Contribution to journalLetterResearchpeer-review

  2. One year of Football Fitness improves L1-L4 BMD, postural balance and muscle strength in women treated for breast cancer

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Self-rated physical fitness and measured cardiorespiratory fitness, muscular strength, and body composition

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Should leisure time sedentary behaviour be replaced with sleep or physical activity for prevention of diabetes?

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Amitriptyline accumulation in tissues after coated activated charcoal hemoperfusion-a randomized controlled animal poisoning model

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Advanced Electrocardiogram Analysis in the Amitriptyline-poisoned Pig Treated with Activated Charcoal Haemoperfusion

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Effects of low-dose recombinant human erythropoietin treatment on cognitive performance

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Citrate, a Ubiquitous Key Metabolite with Regulatory Function in the CNS

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations
Blood passport has been suggested as an indirect tool to detect various kinds of blood manipulations. Autologous blood transfusions are currently undetectable, and the objective of this study was to examine the sensitivities of different blood markers and blood passport approaches in order to determine the best approach to detect autologous blood transfusions. Twenty-nine subjects were transfused with either one (n=8) or three (n=21) bags of autologous blood. Hemoglobin concentration ([Hb]), percentage of reticulocytes (%ret) and hemoglobin mass (Hbmass) were measured 1 day before reinfusion and six times after reinfusion. The sensitivity and specificity of a novel marker, Hbmr (based on Hbmass and %ret), was evaluated together with [Hb], Hbmass and OFF-hr by different passport methods. Our novel Hbmr marker showed superior sensitivity in detecting the highest dosage of transfused blood, with OFF-hr showing equal or superior sensitivities at lower dosages. Hbmr and OFF-hr showed superior but equal sensitivities from 1 to 4 weeks after transfusion compared with [Hb] and Hbmass, with Hbmass being the only tenable prospect to detect acute transfusions. Because autologous blood transfusions can be an acute practice with blood withdrawal and reinfusion within a few days, Hbmass seems to be the only option for revealing this practice.
Original languageEnglish
JournalScandinavian journal of medicine & science in sports
Volume21
Issue number2
Pages (from-to)235-43
Number of pages9
ISSN0905-7188
DOIs
Publication statusPublished - 1 Apr 2011

ID: 32357994