Design and methods of European Ambulance Acute Coronary Syndrome Angiography Trial (EUROMAX): An international randomized open-label ambulance trial of bivalirudin versus standard-of-care anticoagulation in patients with acute ST-segment-elevation myocardial infarction transferred for primary percutaneous coronary intervention

Philippe Gabriel Steg; Arnoud van 't Hof; Peter Clemmensen; Frédéric Lapostolle; Dariusz Dudek; Martial Hamon; Claudio Cavallini; Giovanni Gordini; Kurt Huber; Pierre Coste; Michel Thicoipe; Lutz Nibbe; Jacob Steinmetz; Jurrien Ten Berg; Gerrit Jan Eggink; Uwe Zeymer; Marco Campo Dell' Orto; Vojko Kanic; Efthymios N Deliargyris; Jonathan Day; Diana Schuette; Christian W Hamm; Patrick Goldstein

doi:10.1016/j.ahj.2013.08.025

Design and methods of European Ambulance Acute Coronary Syndrome Angiography Trial (EUROMAX): An international randomized open-label ambulance trial of bivalirudin versus standard-of-care anticoagulation in patients with acute ST-segment-elevation myocardial infarction transferred for primary percutaneous coronary intervention

Philippe Gabriel Steg, Arnoud van 't Hof, Peter Clemmensen, Frédéric Lapostolle, Dariusz Dudek, Martial Hamon, Claudio Cavallini, Giovanni Gordini, Kurt Huber, Pierre Coste, Michel Thicoipe, Lutz Nibbe, Jacob Steinmetz, Jurrien Ten Berg, Gerrit Jan Eggink, Uwe Zeymer, Marco Campo Dell' Orto, Vojko Kanic, Efthymios N Deliargyris, Jonathan DayDiana Schuette, Christian W Hamm, Patrick Goldstein

16 Citations (Scopus)

Abstract

In patients with ST-segment elevation myocardial infarction (STEMI) triaged to primary percutaneous coronary intervention (PCI), anticoagulation often is initiated in the ambulance during transfer to a PCI site. In this prehospital setting, bivalirudin has not been compared with standard-of-care anticoagulation. In addition, it has not been tested in conjunction with the newer P2Y12 inhibitors prasugrel or ticagrelor.

Original language	English
Journal	American Heart Journal
Volume	166
Issue number	6
Pages (from-to)	960-967.e6
ISSN	0002-8703
DOIs	https://doi.org/10.1016/j.ahj.2013.08.025
Publication status	Published - Dec 2013

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Steg, P. G., van 't Hof, A., Clemmensen, P., Lapostolle, F., Dudek, D., Hamon, M., Cavallini, C., Gordini, G., Huber, K., Coste, P., Thicoipe, M., Nibbe, L., Steinmetz, J., Ten Berg, J., Eggink, G. J., Zeymer, U., Campo Dell' Orto, M., Kanic, V., Deliargyris, E. N., ... Goldstein, P. (2013). Design and methods of European Ambulance Acute Coronary Syndrome Angiography Trial (EUROMAX): An international randomized open-label ambulance trial of bivalirudin versus standard-of-care anticoagulation in patients with acute ST-segment-elevation myocardial infarction transferred for primary percutaneous coronary intervention. American Heart Journal, 166(6), 960-967.e6. https://doi.org/10.1016/j.ahj.2013.08.025

Design and methods of European Ambulance Acute Coronary Syndrome Angiography Trial (EUROMAX): An international randomized open-label ambulance trial of bivalirudin versus standard-of-care anticoagulation in patients with acute ST-segment-elevation myocardial infarction transferred for primary percutaneous coronary intervention. / Steg, Philippe Gabriel; van 't Hof, Arnoud; Clemmensen, Peter et al.
In: American Heart Journal, Vol. 166, No. 6, 12.2013, p. 960-967.e6.

Research output: Contribution to journal › Journal article › Research › peer-review

Steg, PG, van 't Hof, A, Clemmensen, P, Lapostolle, F, Dudek, D, Hamon, M, Cavallini, C, Gordini, G, Huber, K, Coste, P, Thicoipe, M, Nibbe, L, Steinmetz, J, Ten Berg, J, Eggink, GJ, Zeymer, U, Campo Dell' Orto, M, Kanic, V, Deliargyris, EN, Day, J, Schuette, D, Hamm, CW & Goldstein, P 2013, 'Design and methods of European Ambulance Acute Coronary Syndrome Angiography Trial (EUROMAX): An international randomized open-label ambulance trial of bivalirudin versus standard-of-care anticoagulation in patients with acute ST-segment-elevation myocardial infarction transferred for primary percutaneous coronary intervention', American Heart Journal, vol. 166, no. 6, pp. 960-967.e6. https://doi.org/10.1016/j.ahj.2013.08.025

Steg PG, van 't Hof A, Clemmensen P, Lapostolle F, Dudek D, Hamon M et al. Design and methods of European Ambulance Acute Coronary Syndrome Angiography Trial (EUROMAX): An international randomized open-label ambulance trial of bivalirudin versus standard-of-care anticoagulation in patients with acute ST-segment-elevation myocardial infarction transferred for primary percutaneous coronary intervention. American Heart Journal. 2013 Dec;166(6):960-967.e6. doi: 10.1016/j.ahj.2013.08.025

Steg, Philippe Gabriel ; van 't Hof, Arnoud ; Clemmensen, Peter et al. / Design and methods of European Ambulance Acute Coronary Syndrome Angiography Trial (EUROMAX) : An international randomized open-label ambulance trial of bivalirudin versus standard-of-care anticoagulation in patients with acute ST-segment-elevation myocardial infarction transferred for primary percutaneous coronary intervention. In: American Heart Journal. 2013 ; Vol. 166, No. 6. pp. 960-967.e6.

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title = "Design and methods of European Ambulance Acute Coronary Syndrome Angiography Trial (EUROMAX): An international randomized open-label ambulance trial of bivalirudin versus standard-of-care anticoagulation in patients with acute ST-segment-elevation myocardial infarction transferred for primary percutaneous coronary intervention",

abstract = "In patients with ST-segment elevation myocardial infarction (STEMI) triaged to primary percutaneous coronary intervention (PCI), anticoagulation often is initiated in the ambulance during transfer to a PCI site. In this prehospital setting, bivalirudin has not been compared with standard-of-care anticoagulation. In addition, it has not been tested in conjunction with the newer P2Y12 inhibitors prasugrel or ticagrelor.",

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AU - Steg, Philippe Gabriel

AU - van 't Hof, Arnoud

AU - Clemmensen, Peter

AU - Lapostolle, Frédéric

AU - Dudek, Dariusz

AU - Hamon, Martial

AU - Cavallini, Claudio

AU - Gordini, Giovanni

AU - Huber, Kurt

AU - Coste, Pierre

AU - Thicoipe, Michel

AU - Nibbe, Lutz

AU - Steinmetz, Jacob

AU - Ten Berg, Jurrien

AU - Eggink, Gerrit Jan

AU - Zeymer, Uwe

AU - Campo Dell' Orto, Marco

AU - Kanic, Vojko

AU - Deliargyris, Efthymios N

AU - Day, Jonathan

AU - Schuette, Diana

AU - Hamm, Christian W

AU - Goldstein, Patrick

PY - 2013/12

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N2 - In patients with ST-segment elevation myocardial infarction (STEMI) triaged to primary percutaneous coronary intervention (PCI), anticoagulation often is initiated in the ambulance during transfer to a PCI site. In this prehospital setting, bivalirudin has not been compared with standard-of-care anticoagulation. In addition, it has not been tested in conjunction with the newer P2Y12 inhibitors prasugrel or ticagrelor.

AB - In patients with ST-segment elevation myocardial infarction (STEMI) triaged to primary percutaneous coronary intervention (PCI), anticoagulation often is initiated in the ambulance during transfer to a PCI site. In this prehospital setting, bivalirudin has not been compared with standard-of-care anticoagulation. In addition, it has not been tested in conjunction with the newer P2Y12 inhibitors prasugrel or ticagrelor.

UR - https://www.scopus.com/pages/publications/84888638493

U2 - 10.1016/j.ahj.2013.08.025

DO - 10.1016/j.ahj.2013.08.025

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C2 - 24268209

SN - 0002-8703

VL - 166

SP - 960-967.e6

JO - American Heart Journal

JF - American Heart Journal

IS - 6

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Abstract

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