Demographics, healthcare utilization and drug use in children and adults with atopic dermatitis in Denmark: a population-based cross-sectional study

Y M F Andersen; A Egeberg; L Skov; J P Thyssen

doi:10.1111/jdv.15424

Demographics, healthcare utilization and drug use in children and adults with atopic dermatitis in Denmark: a population-based cross-sectional study

Y M F Andersen, A Egeberg, L Skov, J P Thyssen

Dermatology and Allergy

Abstract

BACKGROUND: Atopic dermatitis (AD) is a common inflammatory skin condition. While previous publications have examined healthcare expenses, large data regarding patient demographics, healthcare use and drug prescriptions are limited.

OBJECTIVE: To examine demographics, healthcare use and drug prescriptions in children and adults with hospital-diagnosed AD.

METHODS: Danish nationwide registries were cross-linked to access demographic, healthcare and drug prescription data on children and adults with hospital-diagnosed AD (ICD-10 code L20). The diagnostic code for AD used in this study was validated by reviewing medical charts.

RESULTS: We identified 9704 children (time period 1997-2012) and 5558 adults (time period 1997-2007) with hospital-diagnosed AD. The diagnostic code L20 had a positive predictive value of 95%. Among children with AD, a larger proportion came from less resourceful families and had immigrant parents from non-European countries. In adults, we observed an opposite tendency. Topical and systemic antibiotics were used relatively frequent in both children and adults with AD. The use of prednisolone and other systemic anti-inflammatory therapy was substantially higher in adults with AD than in children.

LIMITATIONS: We were unable to identify and describe patients treated by general and private practitioners.

CONCLUSION: There exist significant differences in social predictors for AD and the use of AD medication between children and adults with hospital-diagnosed AD in Denmark. The diagnostic code for AD appears to be valid in Danish registries.

Original language	English
Journal	Journal of the European Academy of Dermatology and Venereology : JEADV
Volume	33
Issue number	6
Pages (from-to)	1133-1142
Number of pages	10
ISSN	0926-9959
DOIs	https://doi.org/10.1111/jdv.15424
Publication status	Published - Jun 2019

Keywords

Adolescent
Adult
Aged
Aged, 80 and over
Child
Child, Preschool
Cross-Sectional Studies
Demography
Denmark/epidemiology
Dermatitis, Atopic/drug therapy
Dermatologic Agents/therapeutic use
Drug Utilization Review
Female
Humans
Infant
Infant, Newborn
Male
Middle Aged
Patient Acceptance of Health Care
Population Surveillance
Registries
Young Adult

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10.1111/jdv.15424

Cite this

Demographics, healthcare utilization and drug use in children and adults with atopic dermatitis in Denmark : a population-based cross-sectional study. / Andersen, Y M F; Egeberg, A ; Skov, L et al.

In: Journal of the European Academy of Dermatology and Venereology : JEADV, Vol. 33, No. 6, 06.2019, p. 1133-1142.

Research output: Contribution to journal › Journal article › Research › peer-review

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abstract = "BACKGROUND: Atopic dermatitis (AD) is a common inflammatory skin condition. While previous publications have examined healthcare expenses, large data regarding patient demographics, healthcare use and drug prescriptions are limited.OBJECTIVE: To examine demographics, healthcare use and drug prescriptions in children and adults with hospital-diagnosed AD.METHODS: Danish nationwide registries were cross-linked to access demographic, healthcare and drug prescription data on children and adults with hospital-diagnosed AD (ICD-10 code L20). The diagnostic code for AD used in this study was validated by reviewing medical charts.RESULTS: We identified 9704 children (time period 1997-2012) and 5558 adults (time period 1997-2007) with hospital-diagnosed AD. The diagnostic code L20 had a positive predictive value of 95%. Among children with AD, a larger proportion came from less resourceful families and had immigrant parents from non-European countries. In adults, we observed an opposite tendency. Topical and systemic antibiotics were used relatively frequent in both children and adults with AD. The use of prednisolone and other systemic anti-inflammatory therapy was substantially higher in adults with AD than in children.LIMITATIONS: We were unable to identify and describe patients treated by general and private practitioners.CONCLUSION: There exist significant differences in social predictors for AD and the use of AD medication between children and adults with hospital-diagnosed AD in Denmark. The diagnostic code for AD appears to be valid in Danish registries.",

keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Cross-Sectional Studies, Demography, Denmark/epidemiology, Dermatitis, Atopic/drug therapy, Dermatologic Agents/therapeutic use, Drug Utilization Review, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Patient Acceptance of Health Care, Population Surveillance, Registries, Young Adult",

author = "Andersen, {Y M F} and A Egeberg and L Skov and Thyssen, {J P}",

note = "{\textcopyright} 2019 European Academy of Dermatology and Venereology.",

year = "2019",

month = jun,

doi = "10.1111/jdv.15424",

language = "English",

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pages = "1133--1142",

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T1 - Demographics, healthcare utilization and drug use in children and adults with atopic dermatitis in Denmark

T2 - a population-based cross-sectional study

AU - Andersen, Y M F

AU - Egeberg, A

AU - Skov, L

AU - Thyssen, J P

PY - 2019/6

Y1 - 2019/6

N2 - BACKGROUND: Atopic dermatitis (AD) is a common inflammatory skin condition. While previous publications have examined healthcare expenses, large data regarding patient demographics, healthcare use and drug prescriptions are limited.OBJECTIVE: To examine demographics, healthcare use and drug prescriptions in children and adults with hospital-diagnosed AD.METHODS: Danish nationwide registries were cross-linked to access demographic, healthcare and drug prescription data on children and adults with hospital-diagnosed AD (ICD-10 code L20). The diagnostic code for AD used in this study was validated by reviewing medical charts.RESULTS: We identified 9704 children (time period 1997-2012) and 5558 adults (time period 1997-2007) with hospital-diagnosed AD. The diagnostic code L20 had a positive predictive value of 95%. Among children with AD, a larger proportion came from less resourceful families and had immigrant parents from non-European countries. In adults, we observed an opposite tendency. Topical and systemic antibiotics were used relatively frequent in both children and adults with AD. The use of prednisolone and other systemic anti-inflammatory therapy was substantially higher in adults with AD than in children.LIMITATIONS: We were unable to identify and describe patients treated by general and private practitioners.CONCLUSION: There exist significant differences in social predictors for AD and the use of AD medication between children and adults with hospital-diagnosed AD in Denmark. The diagnostic code for AD appears to be valid in Danish registries.

AB - BACKGROUND: Atopic dermatitis (AD) is a common inflammatory skin condition. While previous publications have examined healthcare expenses, large data regarding patient demographics, healthcare use and drug prescriptions are limited.OBJECTIVE: To examine demographics, healthcare use and drug prescriptions in children and adults with hospital-diagnosed AD.METHODS: Danish nationwide registries were cross-linked to access demographic, healthcare and drug prescription data on children and adults with hospital-diagnosed AD (ICD-10 code L20). The diagnostic code for AD used in this study was validated by reviewing medical charts.RESULTS: We identified 9704 children (time period 1997-2012) and 5558 adults (time period 1997-2007) with hospital-diagnosed AD. The diagnostic code L20 had a positive predictive value of 95%. Among children with AD, a larger proportion came from less resourceful families and had immigrant parents from non-European countries. In adults, we observed an opposite tendency. Topical and systemic antibiotics were used relatively frequent in both children and adults with AD. The use of prednisolone and other systemic anti-inflammatory therapy was substantially higher in adults with AD than in children.LIMITATIONS: We were unable to identify and describe patients treated by general and private practitioners.CONCLUSION: There exist significant differences in social predictors for AD and the use of AD medication between children and adults with hospital-diagnosed AD in Denmark. The diagnostic code for AD appears to be valid in Danish registries.

KW - Adolescent

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Child

KW - Child, Preschool

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KW - Dermatitis, Atopic/drug therapy

KW - Dermatologic Agents/therapeutic use

KW - Drug Utilization Review

KW - Female

KW - Humans

KW - Infant

KW - Infant, Newborn

KW - Male

KW - Middle Aged

KW - Patient Acceptance of Health Care

KW - Population Surveillance

KW - Registries

KW - Young Adult

U2 - 10.1111/jdv.15424

DO - 10.1111/jdv.15424

M3 - Journal article

C2 - 30633387

VL - 33

SP - 1133

EP - 1142

JO - Journal of the European Academy of Dermatology and Venereology

JF - Journal of the European Academy of Dermatology and Venereology

SN - 0926-9959

IS - 6

ER -

Demographics, healthcare utilization and drug use in children and adults with atopic dermatitis in Denmark: a population-based cross-sectional study

Abstract

Keywords

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