Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Defining "intermittent UVR exposure"

Research output: Contribution to journalJournal articleResearchpeer-review

  1. The half-life of 25(OH)D after UVB exposure depends on gender and vitamin D receptor polymorphism but mainly on the start level

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. UVR: sun, lamps, pigmentation and vitamin D

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Major inter-personal variation in the increase and maximal level of 25-hydroxy vitamin D induced by UVB

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Sun exposure patterns of urban, suburban, and rural children: a dosimetry and diary study of 150 children

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. The background and philosophy behind daylight photodynamic therapy

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Organ transplant recipients express enhanced skin autofluorescence and pigmentation at skin cancer sites

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Photodynamic therapy of necrobiosis lipoidica using methyl aminolevulinate: A retrospective follow-up study

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations
Background: Cutaneous malignant melanoma (CMM) has been associated with “intermittent UVR exposure”, which in previous studies has mainly been assessed by retrospective questionnaire data. Further, there is no uniform definition of the term “intermittent UVR exposure”. Objectives: We aimed to define and quantify “intermittent UVR exposure” by an objective measure. Methods: A broad study population of adults and children had data collected during a summer period. Data were personal UVR dosimetry measurements, from which the number of “intermittent days” was derived, sun behaviour diaries and retrospective questionnaires. Two definitions of intermittent UVR exposure were tested: (1) days when UVR dose exceeded 3 times individual average daily UVR dose, and (2) days when UVR dose exceeded individual constitutive skin type. Measures of nevi and lentigines were used as surrogates for CMM. Results: Using the first definition based solely on UVR dosimetry data we found 1241 “intermittent days” out of a total of 17 277 days (7.2%) among 148 participants. The numbers for nevi and lentigo density were significantly predicted by the number of intermittent days (R2 = 0.15 and R2 = 0.40, p < 0.001). The corresponding numbers for prediction of nevi and lentigo density by retrospective questionnaire data was lower (R2 = 0.11, R2 = 0.26, p < 0.001). Conclusions: We introduce a well-defined objective measure of intermittent UVR exposure. This measure may provide a better prediction of solar skin damage and CMM than retrospective questionnaire data.
Original languageEnglish
JournalPhotochemical and Photobiological Sciences
Volume15
Issue number9
Pages (from-to)1176-82
ISSN1474-905X
Publication statusPublished - 2016

ID: 49761985