Declining incidence of dementia: A national registry-based study over 20 years

Lærke Taudorf; Ane Nørgaard; Sabrina Islamoska; Kasper Jørgensen; Thomas Munk Laursen; Gunhild Waldemar

doi:10.1016/j.jalz.2019.07.006

Declining incidence of dementia: A national registry-based study over 20 years

Lærke Taudorf, Ane Nørgaard, Sabrina Islamoska, Kasper Jørgensen, Thomas Munk Laursen, Gunhild Waldemar

Department of Neurology

41 Citations (Scopus)

Abstract

INTRODUCTION: The aim of this study was to investigate the registry-based national time trends in incidence and prevalence rates of dementia from 1996 to 2015.

METHODS: We assessed annual incidence and prevalence using longitudinal data from nationwide registries on dementia status and demographics on all residents ≥ 65 years old in Denmark.

RESULTS: Our population comprised 2 million people, of whom 152,761 were diagnosed with dementia. The age- and sex-adjusted incidence rate increased, on average, by 9% annually from 1996 to 2003, followed by a 2% annual decline, while total prevalence increased during the whole period.

DISCUSSION: This is the first study to report continuous time trends of incidence and prevalence in an entire national population. The incidence rate has declined steadily since 2003, while the total prevalence is still increasing. Future health care planning on prevention and treatment of dementia should take these findings into account.

Original language	English
Journal	Alzheimer's & dementia : the journal of the Alzheimer's Association
Volume	15
Issue number	11
Pages (from-to)	1383-1391
ISSN	1552-5260
DOIs	https://doi.org/10.1016/j.jalz.2019.07.006
Publication status	Published - Nov 2019

Keywords

Dementia
Epidemiology
Incidence
Nationwide study
Prevalence
Registry study
Time trend

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10.1016/j.jalz.2019.07.006

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abstract = "INTRODUCTION: The aim of this study was to investigate the registry-based national time trends in incidence and prevalence rates of dementia from 1996 to 2015.METHODS: We assessed annual incidence and prevalence using longitudinal data from nationwide registries on dementia status and demographics on all residents ≥ 65 years old in Denmark.RESULTS: Our population comprised 2 million people, of whom 152,761 were diagnosed with dementia. The age- and sex-adjusted incidence rate increased, on average, by 9% annually from 1996 to 2003, followed by a 2% annual decline, while total prevalence increased during the whole period.DISCUSSION: This is the first study to report continuous time trends of incidence and prevalence in an entire national population. The incidence rate has declined steadily since 2003, while the total prevalence is still increasing. Future health care planning on prevention and treatment of dementia should take these findings into account.",

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AU - Taudorf, Lærke

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AU - Islamoska, Sabrina

AU - Jørgensen, Kasper

AU - Laursen, Thomas Munk

AU - Waldemar, Gunhild

PY - 2019/11

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N2 - INTRODUCTION: The aim of this study was to investigate the registry-based national time trends in incidence and prevalence rates of dementia from 1996 to 2015.METHODS: We assessed annual incidence and prevalence using longitudinal data from nationwide registries on dementia status and demographics on all residents ≥ 65 years old in Denmark.RESULTS: Our population comprised 2 million people, of whom 152,761 were diagnosed with dementia. The age- and sex-adjusted incidence rate increased, on average, by 9% annually from 1996 to 2003, followed by a 2% annual decline, while total prevalence increased during the whole period.DISCUSSION: This is the first study to report continuous time trends of incidence and prevalence in an entire national population. The incidence rate has declined steadily since 2003, while the total prevalence is still increasing. Future health care planning on prevention and treatment of dementia should take these findings into account.

AB - INTRODUCTION: The aim of this study was to investigate the registry-based national time trends in incidence and prevalence rates of dementia from 1996 to 2015.METHODS: We assessed annual incidence and prevalence using longitudinal data from nationwide registries on dementia status and demographics on all residents ≥ 65 years old in Denmark.RESULTS: Our population comprised 2 million people, of whom 152,761 were diagnosed with dementia. The age- and sex-adjusted incidence rate increased, on average, by 9% annually from 1996 to 2003, followed by a 2% annual decline, while total prevalence increased during the whole period.DISCUSSION: This is the first study to report continuous time trends of incidence and prevalence in an entire national population. The incidence rate has declined steadily since 2003, while the total prevalence is still increasing. Future health care planning on prevention and treatment of dementia should take these findings into account.

KW - Dementia

KW - Epidemiology

KW - Incidence

KW - Nationwide study

KW - Prevalence

KW - Registry study

KW - Time trend

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Declining incidence of dementia: A national registry-based study over 20 years

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Keywords

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