Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital

DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors

Research output: Contribution to journalJournal articleResearchpeer-review

  1. Pupillary light responses in type 1 and type 2 diabetics with and without retinopathy

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Robust, ECG-based detection of Sleep-disordered breathing in large population-based cohorts

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

PURPOSE: To establish a cohort that enables identification of genomic factors that influence human health and empower increased blood donor health and safe blood transfusions. Human health is complex and involves several factors, a major one being the genomic aspect. The genomic era has resulted in many consortia encompassing large samples sizes, which has proven successful for identifying genetic factors associated with specific traits. However, it remains a big challenge to establish large cohorts that facilitate studies of the interaction between genetic factors, environmental and life-style factors as these change over the course of life. A major obstacle to such endeavours is that it is difficult to revisit participants to retrieve additional information and obtain longitudinal, consecutive measurements.

PARTICIPANTS: Blood donors (n=110 000) have given consent to participate in the Danish Blood Donor Study. The study uses the infrastructure of the Danish blood banks.

FINDINGS TO DATE: The cohort comprises extensive phenotype data and whole genome genotyping data. Further, it is possible to retrieve additional phenotype data from national registries as well as from the donors at future visits, including consecutive measurements.

FUTURE PLANS: To provide new knowledge on factors influencing our health and thus provide a platform for studying the influence of genomic factors on human health, in particular the interaction between environmental and genetic factors.

Original languageEnglish
JournalBMJ Open
Issue number6
Pages (from-to)e028401
Publication statusPublished - 9 Jun 2019

    Research areas

  • genetics, preventive medicine, public health

ID: 57848707