Danish children born with glutamic acid decarboxylase-65 and islet antigen-2 autoantibodies at birth had an increased risk to develop type 1 diabetes

Stefanie Eising, Anita Nilsson, Bendix Carstensen, David M Hougaard, Bent Nørgaard-Pedersen, Jørn Nerup, Ake Lernmark, Flemming Pociot

    8 Citations (Scopus)

    Abstract

    A large, population-based case-control cohort was used to test the hypothesis that glutamic acid decarboxylase-65 (GAD65) and islet antigen-2 autoantibodies (IA-2A) at birth predict type 1 diabetes.
    Original languageEnglish
    JournalEuropean Journal of Endocrinology
    Volume164
    Issue number2
    Pages (from-to)247-52
    Number of pages6
    ISSN0804-4643
    DOIs
    Publication statusPublished - Feb 2011

    Keywords

    • Adolescent
    • Alleles
    • Autoantibodies
    • Case-Control Studies
    • Child
    • Child, Preschool
    • Denmark
    • Diabetes Mellitus, Type 1
    • Genetic Predisposition to Disease
    • Glutamate Decarboxylase
    • Humans
    • Infant
    • Logistic Models
    • Polymerase Chain Reaction
    • Receptor-Like Protein Tyrosine Phosphatases, Class 8
    • Risk
    • Young Adult

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