Cutaneous vasoconstriction affects near-infrared spectroscopy determined cerebral oxygen saturation during administration of norepinephrine

Niels Henrik Breiner Sørensen; Niels H Secher; Christoph Siebenmann; Henning M Bay Nielsen; Matthias Kohl-Bareis; Carsten Lundby; Peter Rasmussen

Cutaneous vasoconstriction affects near-infrared spectroscopy determined cerebral oxygen saturation during administration of norepinephrine

Niels Henrik Breiner Sørensen, Niels H Secher, Christoph Siebenmann, Henning M Bay Nielsen, Matthias Kohl-Bareis, Carsten Lundby, Peter Rasmussen

133 Citations (Scopus)

Abstract

Perioperative optimization of spatially resolved near-infrared spectroscopy determined cerebral frontal lobe oxygenation (scO2) may reduce postoperative morbidity. Norepinephrine is routinely administered to maintain cerebral perfusion pressure and, thereby, cerebral blood flow, but norepinephrine reduces the scO2. We hypothesized that norepinephrine-induced reduction in scO2 is influenced by cutaneous vasoconstriction.

Original language	English
Journal	Anesthesiology News
Volume	117
Issue number	2
Pages (from-to)	263-70
Number of pages	8
ISSN	0747-4679
Publication status	Published - 2012

Keywords

Adult
Anoxia
Blood Pressure
Body Temperature
Brain
Carbon Dioxide
Cerebrovascular Circulation
Humans
Male
Norepinephrine
Oximetry
Oxygen
Skin
Spectroscopy, Near-Infrared
Vasoconstriction
Vasoconstrictor Agents

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Sørensen, N. H. B., Secher, N. H., Siebenmann, C., Nielsen, H. M. B., Kohl-Bareis, M., Lundby, C., & Rasmussen, P. (2012). Cutaneous vasoconstriction affects near-infrared spectroscopy determined cerebral oxygen saturation during administration of norepinephrine. Anesthesiology News, 117(2), 263-70. http://ovidsp.uk.ovid.com.ep.fjernadgang.kb.dk/sp-3.8.0b/ovidweb.cgi?QS2=434f4e1a73d37e8c01e9bb09ab15b392e6ed06758ec4ab603cd62fb5437ee7a168e87914252914db7de9273253eacee919128201e00fe6937fb6c788834908f44c22731569fdbddd41e5aee0043ffbd22f076792899f04deb49f5c453d34319657826b4967a540ebb8f0f91ff0ba94e248d230b8cdb7ea41779a465ad05270c10caf9e03efe8fd16824329ab2c3ad3d6d14d6cd7c3c6d1503848ef1c7e4c83f79d8e95e519feb5878af47de903767ada761713fb8c81a47d555ca1389564d23b84611669b79f03f9a2319efee59fb3a3f8743162feae9cf667de022baeb078c4fb8a7a54614198347730a8503193a0d7

Sørensen, NHB, Secher, NH, Siebenmann, C, Nielsen, HMB, Kohl-Bareis, M, Lundby, C & Rasmussen, P 2012, 'Cutaneous vasoconstriction affects near-infrared spectroscopy determined cerebral oxygen saturation during administration of norepinephrine', Anesthesiology News, vol. 117, no. 2, pp. 263-70. <http://ovidsp.uk.ovid.com.ep.fjernadgang.kb.dk/sp-3.8.0b/ovidweb.cgi?QS2=434f4e1a73d37e8c01e9bb09ab15b392e6ed06758ec4ab603cd62fb5437ee7a168e87914252914db7de9273253eacee919128201e00fe6937fb6c788834908f44c22731569fdbddd41e5aee0043ffbd22f076792899f04deb49f5c453d34319657826b4967a540ebb8f0f91ff0ba94e248d230b8cdb7ea41779a465ad05270c10caf9e03efe8fd16824329ab2c3ad3d6d14d6cd7c3c6d1503848ef1c7e4c83f79d8e95e519feb5878af47de903767ada761713fb8c81a47d555ca1389564d23b84611669b79f03f9a2319efee59fb3a3f8743162feae9cf667de022baeb078c4fb8a7a54614198347730a8503193a0d7>

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title = "Cutaneous vasoconstriction affects near-infrared spectroscopy determined cerebral oxygen saturation during administration of norepinephrine",

abstract = "Perioperative optimization of spatially resolved near-infrared spectroscopy determined cerebral frontal lobe oxygenation (scO2) may reduce postoperative morbidity. Norepinephrine is routinely administered to maintain cerebral perfusion pressure and, thereby, cerebral blood flow, but norepinephrine reduces the scO2. We hypothesized that norepinephrine-induced reduction in scO2 is influenced by cutaneous vasoconstriction.",

keywords = "Adult, Anoxia, Blood Pressure, Body Temperature, Brain, Carbon Dioxide, Cerebrovascular Circulation, Humans, Male, Norepinephrine, Oximetry, Oxygen, Skin, Spectroscopy, Near-Infrared, Vasoconstriction, Vasoconstrictor Agents",

author = "S{\o}rensen, {Niels Henrik Breiner} and Secher, {Niels H} and Christoph Siebenmann and Nielsen, {Henning M Bay} and Matthias Kohl-Bareis and Carsten Lundby and Peter Rasmussen",

year = "2012",

language = "English",

volume = "117",

pages = "263--70",

journal = "Anesthesiology News",

issn = "0747-4679",

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T1 - Cutaneous vasoconstriction affects near-infrared spectroscopy determined cerebral oxygen saturation during administration of norepinephrine

AU - Sørensen, Niels Henrik Breiner

AU - Secher, Niels H

AU - Siebenmann, Christoph

AU - Nielsen, Henning M Bay

AU - Kohl-Bareis, Matthias

AU - Lundby, Carsten

AU - Rasmussen, Peter

PY - 2012

Y1 - 2012

N2 - Perioperative optimization of spatially resolved near-infrared spectroscopy determined cerebral frontal lobe oxygenation (scO2) may reduce postoperative morbidity. Norepinephrine is routinely administered to maintain cerebral perfusion pressure and, thereby, cerebral blood flow, but norepinephrine reduces the scO2. We hypothesized that norepinephrine-induced reduction in scO2 is influenced by cutaneous vasoconstriction.

AB - Perioperative optimization of spatially resolved near-infrared spectroscopy determined cerebral frontal lobe oxygenation (scO2) may reduce postoperative morbidity. Norepinephrine is routinely administered to maintain cerebral perfusion pressure and, thereby, cerebral blood flow, but norepinephrine reduces the scO2. We hypothesized that norepinephrine-induced reduction in scO2 is influenced by cutaneous vasoconstriction.

KW - Adult

KW - Anoxia

KW - Blood Pressure

KW - Body Temperature

KW - Brain

KW - Carbon Dioxide

KW - Cerebrovascular Circulation

KW - Humans

KW - Male

KW - Norepinephrine

KW - Oximetry

KW - Oxygen

KW - Skin

KW - Spectroscopy, Near-Infrared

KW - Vasoconstriction

KW - Vasoconstrictor Agents

M3 - Journal article

C2 - 22739762

SN - 0747-4679

VL - 117

SP - 263

EP - 270

JO - Anesthesiology News

JF - Anesthesiology News

IS - 2

ER -

Cutaneous vasoconstriction affects near-infrared spectroscopy determined cerebral oxygen saturation during administration of norepinephrine

Abstract

Keywords

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