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The Capital Region of Denmark - a part of Copenhagen University Hospital
E-pub ahead of print

Cutaneous adverse reactions to anti-PD-1 treatment - a systematic review

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  1. Tonsillitis and pediatric psoriasis: Cohort and cross-sectional analyses of offspring from the Danish National Birth Cohort

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  2. Chronologic order of appearance of immune-mediated inflammatory diseases relative to diagnosis of psoriasis

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  3. Using a metallic ink pen to assist in the demarcation of skin lesions under reflectance confocal microscopy

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  4. Factors associated with patient-reported importance of skin clearance among adults with psoriasis and atopic dermatitis

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  5. Estimating CDKN2A mutation carrier probability among global familial melanoma cases using GenoMELPREDICT

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  1. Cost of Treating Skin Problems in Patients with Diabetes who Use Insulin Pumps and/or Glucose Sensors

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  2. Dupilumab treatment in two patients with severe allergic contact dermatitis caused by sesquiterpene lactones

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  3. Palmar Eczema From Secondary 2-Hydroxyethyl Methacrylate Exposure-The Artificial Nail Grip Sign

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  4. Severe treatment-resistant acute and recurrent vesicular chronic hand eczema successfully treated with dupilumab

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  5. Allergisk kontakteksem ved anvendelse af insulinpumper og glukosesensorer hos børn med diabetes

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The use of the humanized monoclonal anti-programmed cell death-1 antibodies pembrolizumab and nivolumab as potent anti-cancer therapies is rapidly increasing. However, since their approval numerous cases of cutaneous reactions have been reported. Cutaneous adverse reactions to these agents have yet to be fully characterized and range from non-specific eruptions to recognizable skin manifestations, which may be localized and vary from mild to life-threatening. This systematic review article provides an overview of the various adverse cutaneous reactions to pembrolizumab and nivolumab therapy and offers suggestions for their management.

Original languageEnglish
JournalJournal of the American Academy of Dermatology
ISSN0190-9622
DOIs
Publication statusE-pub ahead of print - 19 Apr 2020

ID: 59742095