Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Crossmodal recruitment of the ventral visual stream in congenital blindness

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Exploring Postoperative Cognitive Dysfunction and Delirium in Noncardiac Surgery Using MRI: A Systematic Review

    Research output: Contribution to journalReviewResearchpeer-review

  2. Thalamocortical Connectivity and Microstructural Changes in Congenital and Late Blindness

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Simultaneous assessment of white matter changes in microstructure and connectedness in the blind brain

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Enhanced chemosensory detection of negative emotions in congenital blindness

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 "Signalosome"

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND)

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Accessibility of cortical regions to focal TES: Dependence on spatial position, safety, and practical constraints

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Neuroimaging Of Cold Allodynia Reveals A Central Disinhibition Mechanism Of Pain

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations
We used functional MRI (fMRI) to test the hypothesis that blind subjects recruit the ventral visual stream during nonhaptic tactile-form recognition. Congenitally blind and blindfolded sighted control subjects were scanned after they had been trained during four consecutive days to perform a tactile-form recognition task with the tongue display unit (TDU). Both groups learned the task at the same rate. In line with our hypothesis, the fMRI data showed that during nonhaptic shape recognition, blind subjects activated large portions of the ventral visual stream, including the cuneus, precuneus, inferotemporal (IT), cortex, lateral occipital tactile vision area (LOtv), and fusiform gyrus. Control subjects activated area LOtv and precuneus but not cuneus, IT and fusiform gyrus. These results indicate that congenitally blind subjects recruit key regions in the ventral visual pathway during nonhaptic tactile shape discrimination. The activation of LOtv by nonhaptic tactile shape processing in blind and sighted subjects adds further support to the notion that this area subserves an abstract or supramodal representation of shape. Together with our previous findings, our data suggest that the segregation of the efferent projections of the primary visual cortex into a dorsal and ventral visual stream is preserved in individuals blind from birth.
Original languageEnglish
JournalNeural Plasticity
Volume2012
Number of pages9
ISSN0792-8483
DOIs
Publication statusPublished - 2012

ID: 36856166