Copeptin and MR-proADM in umbilical cord plasma reflect perinatal stress in neonates born to mothers with diabetes and MR-proANP reflects maternal diabetes

Julie Smith; Karen G Halse; Peter Damm; Marie Ls Lindegaard; Isis Amer-Wåhlin; Steen Hertel; Marianne Johansen; Elisabeth Reinhardt Mathiesen; Lars B Nielsen; Jens P Goetze

doi:10.2217/bmm.12.79

Copeptin and MR-proADM in umbilical cord plasma reflect perinatal stress in neonates born to mothers with diabetes and MR-proANP reflects maternal diabetes

Julie Smith, Karen G Halse, Peter Damm, Marie Ls Lindegaard, Isis Amer-Wåhlin, Steen Hertel, Marianne Johansen, Elisabeth Reinhardt Mathiesen, Lars B Nielsen, Jens P Goetze

7 Citations (Scopus)

Abstract

To examine concentrations of three cardiovascular propeptides in umbilical cord plasma of neonates born to mothers with Type 1, Type 2 and gestational diabetes. Measurement of cardiovascular markers in umbilical cord plasma may potentially help identify neonates at risk of postnatal complications. Neonates born to mothers with diabetes have an increased risk of neonatal morbidity and mortality, and measurement of these new biomarkers may potentially help identify neonates at risk of these complications.

Original language	English
Journal	Biomarkers in Medicine
Volume	7
Issue number	1
Pages (from-to)	139-46
Number of pages	8
ISSN	1752-0363
DOIs	https://doi.org/10.2217/bmm.12.79
Publication status	Published - Feb 2013

Keywords

Acidosis
Adrenomedullin
Adult
Atrial Natriuretic Factor
Biological Markers
Delivery, Obstetric
Diabetes Complications
Diabetes Mellitus
Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2
Diabetes, Gestational
Female
Fetal Blood
Glycopeptides
Humans
Infant, Newborn
Maternal-Fetal Relations
Pregnancy
Protein Precursors
Stress, Psychological

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Smith, J., Halse, K. G., Damm, P., Lindegaard, M. L., Amer-Wåhlin, I., Hertel, S., Johansen, M., Mathiesen, E. R., Nielsen, L. B., & Goetze, J. P. (2013). Copeptin and MR-proADM in umbilical cord plasma reflect perinatal stress in neonates born to mothers with diabetes and MR-proANP reflects maternal diabetes. Biomarkers in Medicine, 7(1), 139-46. https://doi.org/10.2217/bmm.12.79

Smith, J, Halse, KG, Damm, P, Lindegaard, ML, Amer-Wåhlin, I, Hertel, S, Johansen, M , Mathiesen, ER, Nielsen, LB & Goetze, JP 2013, 'Copeptin and MR-proADM in umbilical cord plasma reflect perinatal stress in neonates born to mothers with diabetes and MR-proANP reflects maternal diabetes', Biomarkers in Medicine, vol. 7, no. 1, pp. 139-46. https://doi.org/10.2217/bmm.12.79

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abstract = "To examine concentrations of three cardiovascular propeptides in umbilical cord plasma of neonates born to mothers with Type 1, Type 2 and gestational diabetes. Measurement of cardiovascular markers in umbilical cord plasma may potentially help identify neonates at risk of postnatal complications. Neonates born to mothers with diabetes have an increased risk of neonatal morbidity and mortality, and measurement of these new biomarkers may potentially help identify neonates at risk of these complications.",

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AU - Smith, Julie

AU - Halse, Karen G

AU - Damm, Peter

AU - Lindegaard, Marie Ls

AU - Amer-Wåhlin, Isis

AU - Hertel, Steen

AU - Johansen, Marianne

AU - Mathiesen, Elisabeth Reinhardt

AU - Nielsen, Lars B

AU - Goetze, Jens P

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AB - To examine concentrations of three cardiovascular propeptides in umbilical cord plasma of neonates born to mothers with Type 1, Type 2 and gestational diabetes. Measurement of cardiovascular markers in umbilical cord plasma may potentially help identify neonates at risk of postnatal complications. Neonates born to mothers with diabetes have an increased risk of neonatal morbidity and mortality, and measurement of these new biomarkers may potentially help identify neonates at risk of these complications.

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KW - Adrenomedullin

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KW - Atrial Natriuretic Factor

KW - Biological Markers

KW - Delivery, Obstetric

KW - Diabetes Complications

KW - Diabetes Mellitus

KW - Diabetes Mellitus, Type 1

KW - Diabetes Mellitus, Type 2

KW - Diabetes, Gestational

KW - Female

KW - Fetal Blood

KW - Glycopeptides

KW - Humans

KW - Infant, Newborn

KW - Maternal-Fetal Relations

KW - Pregnancy

KW - Protein Precursors

KW - Stress, Psychological

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U2 - 10.2217/bmm.12.79

DO - 10.2217/bmm.12.79

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SN - 1752-0363

VL - 7

SP - 139

EP - 146

JO - Biomarkers in Medicine

JF - Biomarkers in Medicine

IS - 1

ER -

Copeptin and MR-proADM in umbilical cord plasma reflect perinatal stress in neonates born to mothers with diabetes and MR-proANP reflects maternal diabetes

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Keywords

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