TY - JOUR
T1 - Continuous Right Ventricular Pressure Monitoring in Cardiac Surgery
AU - Denault, André
AU - Couture, Etienne J
AU - Perry, Tjorvi
AU - Saade, Elena
AU - Calderone, Alexander
AU - Zeng, Yu Hao
AU - Scherb, Daniel
AU - Moses, Kevin
AU - Potes, Cristhian
AU - Hammoud, Ali
AU - Beaubien-Souligny, William
AU - Elmi-Sarabi, Mahsa
AU - Grønlykke, Lars
AU - Lamarche, Yoan
AU - Lebon, Jean-Sébastien
AU - Rousseau-Saine, Nicolas
AU - Desjardins, Georges
AU - Rochon, Antoine
N1 - Copyright © 2024 Elsevier Inc. All rights reserved.
PY - 2024
Y1 - 2024
N2 - OBJECTIVE: Right ventricular (RV) dysfunction in cardiac surgery can lead to RV failure, which is associated with increased morbidity and mortality. Abnormal RV function can be identified using RV pressure monitoring. The primary objective of the study is to determine the proportion of patients with abnormal RV early to end-diastole diastolic pressure gradient (RVDPG) and abnormal RV end-diastolic pressure (RVEDP) before initiation and after cardiopulmonary bypass (CPB) separation. The secondary objective is to evaluate if RVDPG before CPB initiation is associated with difficult and complex separation from CPB, RV dysfunction, and failure at the end of cardiac surgery.DESIGN: Prospective study.SETTING: Tertiary care cardiac institute.PARTICIPANTS: Cardiac surgical patients.INTERVENTION: Cardiac surgery.MEASUREMENTS AND MAIN RESULTS: Automated electronic quantification of RVDPG and RVEDP were obtained. Hemodynamic measurements were correlated with cardiac and extracardiac parameters from transesophageal echocardiography and postoperative complications. Abnormal RVDPG was present in 80% of the patients (n = 105) at baseline, with a mean RVEDP of 14.2 ± 3.9 mmHg. Patients experienced an RVDPG > 4 mmHg for a median duration of 50.2% of the intraoperative period before CPB initiation and 60.6% after CPB separation. A total of 46 (43.8%) patients had difficult/complex separation from CPB, 18 (38.3%) patients had RV dysfunction, and 8 (17%) had RV failure. Abnormal RVDPG before CPB was not associated with postoperative outcome.CONCLUSION: Elevated RVDPG and RVEDP are common in cardiac surgery. RVDPG and RVEDP before CPB initiation are not associated with RV dysfunction and failure but can be used to diagnose them.
AB - OBJECTIVE: Right ventricular (RV) dysfunction in cardiac surgery can lead to RV failure, which is associated with increased morbidity and mortality. Abnormal RV function can be identified using RV pressure monitoring. The primary objective of the study is to determine the proportion of patients with abnormal RV early to end-diastole diastolic pressure gradient (RVDPG) and abnormal RV end-diastolic pressure (RVEDP) before initiation and after cardiopulmonary bypass (CPB) separation. The secondary objective is to evaluate if RVDPG before CPB initiation is associated with difficult and complex separation from CPB, RV dysfunction, and failure at the end of cardiac surgery.DESIGN: Prospective study.SETTING: Tertiary care cardiac institute.PARTICIPANTS: Cardiac surgical patients.INTERVENTION: Cardiac surgery.MEASUREMENTS AND MAIN RESULTS: Automated electronic quantification of RVDPG and RVEDP were obtained. Hemodynamic measurements were correlated with cardiac and extracardiac parameters from transesophageal echocardiography and postoperative complications. Abnormal RVDPG was present in 80% of the patients (n = 105) at baseline, with a mean RVEDP of 14.2 ± 3.9 mmHg. Patients experienced an RVDPG > 4 mmHg for a median duration of 50.2% of the intraoperative period before CPB initiation and 60.6% after CPB separation. A total of 46 (43.8%) patients had difficult/complex separation from CPB, 18 (38.3%) patients had RV dysfunction, and 8 (17%) had RV failure. Abnormal RVDPG before CPB was not associated with postoperative outcome.CONCLUSION: Elevated RVDPG and RVEDP are common in cardiac surgery. RVDPG and RVEDP before CPB initiation are not associated with RV dysfunction and failure but can be used to diagnose them.
KW - Aged
KW - Cardiac Surgical Procedures/adverse effects
KW - Cardiopulmonary Bypass/methods
KW - Echocardiography, Transesophageal/methods
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Monitoring, Intraoperative/methods
KW - Prospective Studies
KW - Ventricular Dysfunction, Right/physiopathology
KW - Ventricular Function, Right/physiology
KW - Ventricular Pressure/physiology
KW - right ventricular pressure monitoring
KW - cardiac anesthesiology
KW - hemodynamic
KW - hemodynamic monitoring
KW - right ventricle
KW - cardiac surgery
UR - http://www.scopus.com/inward/record.url?scp=85195505107&partnerID=8YFLogxK
U2 - 10.1053/j.jvca.2024.04.025
DO - 10.1053/j.jvca.2024.04.025
M3 - Journal article
C2 - 38862285
SN - 1053-0770
VL - 38
SP - 1673
EP - 1682
JO - Journal of Cardiothoracic and Vascular Anesthesia
JF - Journal of Cardiothoracic and Vascular Anesthesia
IS - 8
ER -