Considerable haplotype diversity within the 23kb encompassing the ADH7 gene

Yi Han, Hiroki Oota, Michael V Osier, Andrew J Pakstis, William C Speed, Adekunle Odunsi, Friday Okonofua, Sylvester L B Kajuna, Nganyirwa J Karoma, Selemani Kungulilo, Elena Grigorenko, Olga V Zhukova, Batsheva Bonne-Tamir, Ru-B Lu, Josef Parnas, Leslie O Schulz, Judith R Kidd, Kenneth K Kidd

    18 Citations (Scopus)


    Of the seven known human alcohol dehydrogenase (ADH) genes, the non-liver expressed ADH7 gene codes for the enzyme with the highest maximal activity for ethanol. Previous study from our laboratory has suggested that ADH7 has an epistatic role for protection against alcoholism based on a single ADH7 SNP.
    Original languageEnglish
    JournalAlcoholism: Clinical and Experimental Research
    Issue number12
    Pages (from-to)2091-100
    Number of pages10
    Publication statusPublished - 2005


    • Alcohol Dehydrogenase
    • Alcoholism
    • Alleles
    • DNA
    • Ethnic Groups
    • Gene Frequency
    • Genotype
    • Haplotypes
    • Humans
    • Linkage Disequilibrium
    • Polymorphism, Single Nucleotide


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