Comparison of metformin and insulin versus insulin alone for type 2 diabetes: systematic review of randomised clinical trials with meta-analyses and trial sequential analyses

Bianca Hemmingsen, Louise Lundby Christensen, Jørn Wetterslev, Allan Vaag, Christian Gluud, Søren Lund, Thomas Almdal

89 Citations (Scopus)

Abstract

To compare the benefits and harms of metformin and insulin versus insulin alone as reported in randomised clinical trials of patients with type 2 diabetes.
Original languageEnglish
JournalB M J
Volume344
Pages (from-to)e1771
ISSN0959-8146
DOIs
Publication statusPublished - 2012

Keywords

  • Bias (Epidemiology)
  • Cardiovascular Diseases
  • Diabetes Mellitus, Type 2
  • Drug Therapy, Combination
  • Hemoglobin A, Glycosylated
  • Humans
  • Hypoglycemic Agents
  • Insulin
  • Metformin
  • Randomized Controlled Trials as Topic
  • Weight Gain

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