Comparison of a soluble co-formulation of insulin degludec/insulin aspart vs biphasic insulin aspart 30 in type 2 diabetes: a randomised trial

Leo Niskanen; Lawrence A Leiter; Edward Franek; Jianping Weng; Taner Damci; Manuel Muñoz-Torres; Jean-Paul Donnet; Lars Endahl; Trine Vang Skjøth; Allan Vaag

doi:10.1530/EJE-12-0293

Comparison of a soluble co-formulation of insulin degludec/insulin aspart vs biphasic insulin aspart 30 in type 2 diabetes: a randomised trial

Leo Niskanen, Lawrence A Leiter, Edward Franek, Jianping Weng, Taner Damci, Manuel Muñoz-Torres, Jean-Paul Donnet, Lars Endahl, Trine Vang Skjøth, Allan Vaag

58 Citations (Scopus)

Abstract

Insulin degludec/insulin aspart (IDegAsp) is a soluble co-formulation of insulin degludec (70%) and insulin aspart (IAsp: 30%). Here, we compare the efficacy and safety of IDegAsp, an alternative IDegAsp formulation (AF: containing 45% IAsp), and biphasic IAsp 30 (BIAsp 30).

Original language	English
Journal	European Journal of Endocrinology
Volume	167
Issue number	2
Pages (from-to)	287-94
Number of pages	8
ISSN	0804-4643
DOIs	https://doi.org/10.1530/EJE-12-0293
Publication status	Published - 2012

Keywords

Adolescent
Adult
Aged
Biphasic Insulins
Chemistry, Pharmaceutical
Diabetes Mellitus, Type 2
Drug Administration Schedule
Drug Combinations
Female
Hemoglobin A, Glycosylated
Humans
Hypoglycemic Agents
Insulin Aspart
Insulin, Isophane
Insulin, Long-Acting
Male
Metformin
Middle Aged
Solubility
Treatment Outcome
Young Adult

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10.1530/EJE-12-0293

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Niskanen, L., Leiter, L. A., Franek, E., Weng, J., Damci, T., Muñoz-Torres, M., Donnet, J.-P., Endahl, L., Skjøth, T. V., & Vaag, A. (2012). Comparison of a soluble co-formulation of insulin degludec/insulin aspart vs biphasic insulin aspart 30 in type 2 diabetes: a randomised trial. European Journal of Endocrinology, 167(2), 287-94. https://doi.org/10.1530/EJE-12-0293

Niskanen, L, Leiter, LA, Franek, E, Weng, J, Damci, T, Muñoz-Torres, M, Donnet, J-P, Endahl, L, Skjøth, TV & Vaag, A 2012, 'Comparison of a soluble co-formulation of insulin degludec/insulin aspart vs biphasic insulin aspart 30 in type 2 diabetes: a randomised trial', European Journal of Endocrinology, vol. 167, no. 2, pp. 287-94. https://doi.org/10.1530/EJE-12-0293

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abstract = "Insulin degludec/insulin aspart (IDegAsp) is a soluble co-formulation of insulin degludec (70%) and insulin aspart (IAsp: 30%). Here, we compare the efficacy and safety of IDegAsp, an alternative IDegAsp formulation (AF: containing 45% IAsp), and biphasic IAsp 30 (BIAsp 30).",

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AU - Niskanen, Leo

AU - Leiter, Lawrence A

AU - Franek, Edward

AU - Weng, Jianping

AU - Damci, Taner

AU - Muñoz-Torres, Manuel

AU - Donnet, Jean-Paul

AU - Endahl, Lars

AU - Skjøth, Trine Vang

AU - Vaag, Allan

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KW - Aged

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KW - Chemistry, Pharmaceutical

KW - Diabetes Mellitus, Type 2

KW - Drug Administration Schedule

KW - Drug Combinations

KW - Female

KW - Hemoglobin A, Glycosylated

KW - Humans

KW - Hypoglycemic Agents

KW - Insulin Aspart

KW - Insulin, Isophane

KW - Insulin, Long-Acting

KW - Male

KW - Metformin

KW - Middle Aged

KW - Solubility

KW - Treatment Outcome

KW - Young Adult

U2 - 10.1530/EJE-12-0293

DO - 10.1530/EJE-12-0293

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VL - 167

SP - 287

EP - 294

JO - European Journal of Endocrinology

JF - European Journal of Endocrinology

IS - 2

ER -

Comparison of a soluble co-formulation of insulin degludec/insulin aspart vs biphasic insulin aspart 30 in type 2 diabetes: a randomised trial

Abstract

Keywords

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