Comparing Seizure-Related Death and Suicide in Younger Adults with Epilepsy

Marius Kløvgaard; Thomas H Lynge; Ioannis Tsiropoulos; Peter V Uldall; Jytte Banner; Bo G Winkel; Philippe Ryvlin; Jacob Tfelt-Hansen; Anne Sabers

doi:10.1002/ana.26227

Comparing Seizure-Related Death and Suicide in Younger Adults with Epilepsy

Marius Kløvgaard, Thomas H Lynge, Ioannis Tsiropoulos, Peter V Uldall, Jytte Banner, Bo G Winkel, Philippe Ryvlin, Jacob Tfelt-Hansen, Anne Sabers

4 Citations (Scopus)

Abstract

Younger adults with epilepsy have an increased mortality. Some deaths are seizure-related, for example, sudden unexpected death in epilepsy (SUDEP), whereas others, for example, suicide, have multiple causes, including adverse effects of the treatment on mood. In this retrospective population-based study of all Danish persons with epilepsy aged 18 to 49 years during 2007 to 2009 we evaluated the risk of death from seizures and suicide. SUDEP comprised 82.7% of all seizure-related death. Younger adults with epilepsy had an 8.3-fold increased risk of death from seizure-related causes compared with suicide. This underpins the importance of effective seizure control in preventing premature death. ANN NEUROL 2021;90:983-987.

Original language	English
Journal	Annals of Neurology
Volume	90
Issue number	6
Pages (from-to)	983-987
Number of pages	5
ISSN	0364-5134
DOIs	https://doi.org/10.1002/ana.26227
Publication status	Published - Dec 2021

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10.1002/ana.26227

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abstract = "Younger adults with epilepsy have an increased mortality. Some deaths are seizure-related, for example, sudden unexpected death in epilepsy (SUDEP), whereas others, for example, suicide, have multiple causes, including adverse effects of the treatment on mood. In this retrospective population-based study of all Danish persons with epilepsy aged 18 to 49 years during 2007 to 2009 we evaluated the risk of death from seizures and suicide. SUDEP comprised 82.7% of all seizure-related death. Younger adults with epilepsy had an 8.3-fold increased risk of death from seizure-related causes compared with suicide. This underpins the importance of effective seizure control in preventing premature death. ANN NEUROL 2021;90:983-987.",

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AU - Kløvgaard, Marius

AU - Lynge, Thomas H

AU - Tsiropoulos, Ioannis

AU - Uldall, Peter V

AU - Banner, Jytte

AU - Winkel, Bo G

AU - Ryvlin, Philippe

AU - Tfelt-Hansen, Jacob

AU - Sabers, Anne

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AB - Younger adults with epilepsy have an increased mortality. Some deaths are seizure-related, for example, sudden unexpected death in epilepsy (SUDEP), whereas others, for example, suicide, have multiple causes, including adverse effects of the treatment on mood. In this retrospective population-based study of all Danish persons with epilepsy aged 18 to 49 years during 2007 to 2009 we evaluated the risk of death from seizures and suicide. SUDEP comprised 82.7% of all seizure-related death. Younger adults with epilepsy had an 8.3-fold increased risk of death from seizure-related causes compared with suicide. This underpins the importance of effective seizure control in preventing premature death. ANN NEUROL 2021;90:983-987.

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Comparing Seizure-Related Death and Suicide in Younger Adults with Epilepsy

Abstract

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