Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Co-morbidities in severe asthma: Clinical impact and management

Research output: Contribution to journalReviewResearchpeer-review

  1. Increased risk of major adverse cardiac events following the onset of acute exacerbations of COPD

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Importance of oesophageal ultrasound in mediastinal staging of lung cancer

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Novel assessment tool to detect breathing pattern disorder in patients with refractory asthma

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Predictive value of eosinophils and neutrophils on clinical effects of ICS in COPD

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. International Severe Asthma Registry: Mission Statement

    Research output: Contribution to journalReviewResearchpeer-review

  2. NORDSTAR - Paving the way for a new era in asthma research

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Clinical characteristics of the BREATHE cohort - a real-life study on patients with asthma and COPD

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Characteristics and treatment regimens across ERS SHARP severe asthma registries

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

Patients with severe asthma represent a minority of the total asthma population, but carry a majority of the morbidity and healthcare costs. Achieving better asthma control in this group of patients is therefore of key importance. Systematic assessment of patients with possible severe asthma to identify treatment barriers and triggers of asthma symptoms, including co-morbidities, improves asthma control and reduces healthcare costs and is recommended by international guidelines on management of severe asthma. This review provides the clinician with an overview of the prevalence and clinical impact of the most common co-morbidities in severe asthma, including chronic rhinosinusitis, nasal polyposis, allergic rhinitis, dysfunctional breathing, vocal cord dysfunction, anxiety and depression, obesity, obstructive sleep apnoea syndrome (OSAS), gastroesophageal reflux disease (GERD), bronchiectasis, allergic bronchopulmonary aspergillosis (ABPA) and eosinophilic granulomatous with polyangiitis (EGPA). Furthermore, the review offers a summary of recommended diagnostic and management approaches for each co-morbidity. Finally, the review links co-morbid conditions to specific phenotypes of severe asthma, in order to guide the clinician on which co-morbidities to look for in specific patients.

Original languageEnglish
JournalRespirology (Carlton, Vic.)
Volume22
Issue number4
Pages (from-to)651-661
Number of pages11
ISSN1323-7799
DOIs
Publication statusPublished - May 2017

    Research areas

  • Journal Article, Review

ID: 51980335