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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Combination of autoantibodies against different histone proteins influences complement-dependent phagocytosis of necrotic cell material by polymorphonuclear leukocytes in systemic lupus erythematosus

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  1. Galectin-3-binding protein is a novel predictor of venous thromboembolism in systemic lupus erythematosus

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Early life body size, growth and risks of systemic lupus erythematosus - A large Danish observational cohort study

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  3. Hydroxychloroquine in patients with rheumatic diseases during the COVID-19 pandemic: a letter to clinicians

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  • Birgitta Gullstrand
  • Malin H Lefort
  • Helena Tydén
  • Andreas Jönsen
  • Christian Lood
  • Asa Johansson
  • Søren Jacobsen
  • Lennart Truedsson
  • Anders A Bengtsson
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Polymorphonuclear leukocytes (PMN) with autoantibody-coated engulfed necrotic cell material (NC) are frequently seen in systemic lupus erythematosus (SLE). We evaluated the roles of complement, different antihistone antibodies (anti-H ab), and oxidative burst in the phagocytosis of NC by PMN, as well as association to disease activity and clinical phenotype in SLE.
Original languageEnglish
JournalJournal of Rheumatology
Volume39
Issue number8
Pages (from-to)1619-27
Number of pages9
ISSN0315-162X
DOIs
Publication statusPublished - 2012

    Research areas

  • Adolescent, Adult, Aged, Aged, 80 and over, Autoantibodies, Complement System Proteins, Female, Histones, Humans, Lupus Erythematosus, Systemic, Male, Middle Aged, Necrosis, Neutrophils, Phagocytosis, Prospective Studies

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