Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa

Gloria Herrmann; Liang Yang; Hong Wu; Zhijun Song; Hengzhuang Wang; Niels Høiby; Martina Ulrich; Søren Molin; Joachim Riethmüller; Gerd Döring

doi:10.1086/656788

Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa

Gloria Herrmann, Liang Yang, Hong Wu, Zhijun Song, Hengzhuang Wang, Niels Høiby, Martina Ulrich, Søren Molin, Joachim Riethmüller, Gerd Döring

Department of Clinical Microbiology

187 Citations (Scopus)

Abstract

Antibiotic combination therapy might be more efficient than single antibiotics to combat Pseudomonas aeruginosa biofilms in the airways of patients with cystic fibrosis. We tested the ability of colistin sulphate-tobramycin combinations and single antibiotics to kill P. aeruginosa biofilms.

Original language	English
Journal	Journal of Infectious Diseases
Volume	202
Issue number	10
Pages (from-to)	1585-92
Number of pages	8
ISSN	0022-1899
DOIs	https://doi.org/10.1086/656788
Publication status	Published - 15 Nov 2010

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title = "Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa",

abstract = "Antibiotic combination therapy might be more efficient than single antibiotics to combat Pseudomonas aeruginosa biofilms in the airways of patients with cystic fibrosis. We tested the ability of colistin sulphate-tobramycin combinations and single antibiotics to kill P. aeruginosa biofilms.",

author = "Gloria Herrmann and Liang Yang and Hong Wu and Zhijun Song and Hengzhuang Wang and Niels H{\o}iby and Martina Ulrich and S{\o}ren Molin and Joachim Riethm{\"u}ller and Gerd D{\"o}ring",

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T1 - Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa

AU - Herrmann, Gloria

AU - Yang, Liang

AU - Wu, Hong

AU - Song, Zhijun

AU - Wang, Hengzhuang

AU - Høiby, Niels

AU - Ulrich, Martina

AU - Molin, Søren

AU - Riethmüller, Joachim

AU - Döring, Gerd

PY - 2010/11/15

Y1 - 2010/11/15

N2 - Antibiotic combination therapy might be more efficient than single antibiotics to combat Pseudomonas aeruginosa biofilms in the airways of patients with cystic fibrosis. We tested the ability of colistin sulphate-tobramycin combinations and single antibiotics to kill P. aeruginosa biofilms.

AB - Antibiotic combination therapy might be more efficient than single antibiotics to combat Pseudomonas aeruginosa biofilms in the airways of patients with cystic fibrosis. We tested the ability of colistin sulphate-tobramycin combinations and single antibiotics to kill P. aeruginosa biofilms.

U2 - 10.1086/656788

DO - 10.1086/656788

M3 - Journal article

C2 - 20942647

SN - 0022-1899

VL - 202

SP - 1585

EP - 1592

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

IS - 10

ER -

Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa

Abstract

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