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Cognitive performance in elderly women: significance of the 19bp insertion/deletion polymorphism in the 5' flank of the dopamine beta-hydroxylase gene, educational level, body fat measures, serum triglyceride, alcohol consumption and age

Mads Togsverd, Thomas M Werge, Laszlo B Tankó, Yu Zhao Bagger, George G Qin, Thomas Hansen, Claus Christiansen, Henrik B Rasmussen

14 Citations (Scopus)

Abstract

Genetic and environmental factors influence cognitive aging. The gene encoding dopamine beta-hydroxylase (DBH) could be one such factor since this hydroxylase converts dopamine to norepinephrine both of which are involved in cognition regulation.
Original languageEnglish
JournalInternational Journal of Geriatric Psychiatry
Volume22
Issue number9
Pages (from-to)883-9
Number of pages7
ISSN0885-6230
DOIs
Publication statusPublished - 2007

Keywords

  • 5' Untranslated Regions
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Alcohol Drinking
  • Body Composition
  • Cognition
  • Cross-Sectional Studies
  • Dopamine beta-Hydroxylase
  • Educational Status
  • Female
  • Genetic Predisposition to Disease
  • Genotype
  • Humans
  • Lipids
  • Mental Status Schedule
  • Middle Aged
  • Multivariate Analysis
  • Polymorphism, Genetic
  • Psychological Tests
  • Regression Analysis
  • Risk Factors
  • Triglycerides

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