Abstract
UNLABELLED: Clonidine is an alpha2-adrenergic agonist with analgetic properties. Due to its side-effects, the drug is administered via the epidural or spinal route. A literature search yielded nine controlled studies on clonidine as a supplemental drug in the epidural or spinal treatment of cancer pain. These studies were systematically reviewed to evaluate the evidence of efficacy in patients with cancer pain.
CONCLUSION: Despite weak evidence, clonidine may be a useful adjunct in epidural or spinal morphine therapy of cancer pain.
| Translated title of the contribution | Clonidine in the treatment of cancer pain |
|---|---|
| Original language | Danish |
| Journal | Ugeskrift for Laeger |
| Volume | 170 |
| Issue number | 45 |
| Pages (from-to) | 3650-3 |
| Number of pages | 4 |
| ISSN | 0041-5782 |
| Publication status | Published - 3 Nov 2008 |
| Externally published | Yes |