Clinical use of cerebral oximetry in extremely preterm infants is feasible

Simon Hyttel-Sørensen; Topun Austin; Frank van Bel; Manon Benders; Olivier Claris; Eugene M Dempsey; Monica Fumagalli; Christian Gluud; Cornelia Hagmann; Lena Hellström-Westas; Petra Lemmers; Gunnar Naulaers; Wim van Oeveren; Adelina Pellicer; Gerhard Pichler; Claudia Roll; Lina Saem Støy; Martin Wolf; Gorm Greisen

Clinical use of cerebral oximetry in extremely preterm infants is feasible

Simon Hyttel-Sørensen, Topun Austin, Frank van Bel, Manon Benders, Olivier Claris, Eugene M Dempsey, Monica Fumagalli, Christian Gluud, Cornelia Hagmann, Lena Hellström-Westas, Petra Lemmers, Gunnar Naulaers, Wim van Oeveren, Adelina Pellicer, Gerhard Pichler, Claudia Roll, Lina Saem Støy, Martin Wolf, Gorm Greisen

36 Citations (Scopus)

Abstract

The research programme Safeguarding the Brains of our smallest Children (SafeBoosC) aims to test the benefits and harms of cerebral near-infrared spectroscopy (NIRS) oximetry in infants born before 28 weeks of gestation. In a phase II trial, infants will be randomised to visible cerebral NIRS oximetry with pre-specified treatment guidelines compared to standard care with blinded NIRS-monitoring. The primary outcome is duration multiplied with the extent outside the normal range of regional tissue oxygen saturation of haemoglobin (rStO2) of 55 to 85% in percentage hours (burden). This study was a pilot of the Visible -Oximetry Group.

Original language	English
Journal	Danish Medical Journal
Volume	60
Issue number	1
Pages (from-to)	A4533
Publication status	Published - 2013

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Hyttel-Sørensen, S., Austin, T., van Bel, F., Benders, M., Claris, O., Dempsey, E. M., Fumagalli, M., Gluud, C., Hagmann, C., Hellström-Westas, L., Lemmers, P., Naulaers, G., Oeveren, W. V., Pellicer, A., Pichler, G., Roll, C., Støy, L. S., Wolf, M., & Greisen, G. (2013). Clinical use of cerebral oximetry in extremely preterm infants is feasible. Danish Medical Journal, 60(1), A4533.

Hyttel-Sørensen, S, Austin, T, van Bel, F, Benders, M, Claris, O, Dempsey, EM, Fumagalli, M, Gluud, C, Hagmann, C, Hellström-Westas, L, Lemmers, P, Naulaers, G, Oeveren, WV, Pellicer, A, Pichler, G, Roll, C, Støy, LS, Wolf, M & Greisen, G 2013, 'Clinical use of cerebral oximetry in extremely preterm infants is feasible', Danish Medical Journal, vol. 60, no. 1, pp. A4533.

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abstract = "The research programme Safeguarding the Brains of our smallest Children (SafeBoosC) aims to test the benefits and harms of cerebral near-infrared spectroscopy (NIRS) oximetry in infants born before 28 weeks of gestation. In a phase II trial, infants will be randomised to visible cerebral NIRS oximetry with pre-specified treatment guidelines compared to standard care with blinded NIRS-monitoring. The primary outcome is duration multiplied with the extent outside the normal range of regional tissue oxygen saturation of haemoglobin (rStO2) of 55 to 85\% in percentage hours (burden). This study was a pilot of the Visible -Oximetry Group.",

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AU - Hyttel-Sørensen, Simon

AU - Austin, Topun

AU - van Bel, Frank

AU - Benders, Manon

AU - Claris, Olivier

AU - Dempsey, Eugene M

AU - Fumagalli, Monica

AU - Gluud, Christian

AU - Hagmann, Cornelia

AU - Hellström-Westas, Lena

AU - Lemmers, Petra

AU - Naulaers, Gunnar

AU - Oeveren, Wim van

AU - Pellicer, Adelina

AU - Pichler, Gerhard

AU - Roll, Claudia

AU - Støy, Lina Saem

AU - Wolf, Martin

AU - Greisen, Gorm

PY - 2013

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N2 - The research programme Safeguarding the Brains of our smallest Children (SafeBoosC) aims to test the benefits and harms of cerebral near-infrared spectroscopy (NIRS) oximetry in infants born before 28 weeks of gestation. In a phase II trial, infants will be randomised to visible cerebral NIRS oximetry with pre-specified treatment guidelines compared to standard care with blinded NIRS-monitoring. The primary outcome is duration multiplied with the extent outside the normal range of regional tissue oxygen saturation of haemoglobin (rStO2) of 55 to 85% in percentage hours (burden). This study was a pilot of the Visible -Oximetry Group.

AB - The research programme Safeguarding the Brains of our smallest Children (SafeBoosC) aims to test the benefits and harms of cerebral near-infrared spectroscopy (NIRS) oximetry in infants born before 28 weeks of gestation. In a phase II trial, infants will be randomised to visible cerebral NIRS oximetry with pre-specified treatment guidelines compared to standard care with blinded NIRS-monitoring. The primary outcome is duration multiplied with the extent outside the normal range of regional tissue oxygen saturation of haemoglobin (rStO2) of 55 to 85% in percentage hours (burden). This study was a pilot of the Visible -Oximetry Group.

UR - https://www.scopus.com/pages/publications/84873248511

M3 - Journal article

C2 - 23340184

SN - 1603-9629

VL - 60

SP - A4533

JO - Danish Medical Journal

JF - Danish Medical Journal

IS - 1

ER -

Clinical use of cerebral oximetry in extremely preterm infants is feasible

Abstract

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