Clinical impact of leukemic blast heterogeneity at diagnosis in cytogenetic intermediate-risk acute myeloid leukemia

Marianne Hutchings Hoffmann, Tobias Wirenfeldt Klausen, Martin Boegsted, Steffen Falgreen Larsen, Alexander Schmitz, Eva Birgitte Leinøe, Kjeld Schmiegelow, Henrik Hasle, Olav Jonas Bergmann, Suzette Sorensen, Mette Nyegaard, Karen Dybkaer, Hans Erik Johnsen

11 Citations (Scopus)

Abstract

Individual cellular heterogeneity within the acute myeloid leukemia (AML) bone marrow samples can be observed by multi parametric flow cytometry analysis (MFC) indicating that immunophenotypic screening for leukemic blast subsets may have prognostic impact.
Original languageEnglish
JournalCytometry. Part B: Clinical Cytometry
Volume82
Issue number3
Pages (from-to)123-31
Number of pages9
ISSN1552-4949
DOIs
Publication statusPublished - 2012

Keywords

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antigens, CD14
  • Antigens, CD45
  • Antigens, CD58
  • Antigens, Surface
  • Bone Marrow Cells
  • Bone Marrow Examination
  • Child
  • Child, Preschool
  • Female
  • Flow Cytometry
  • Humans
  • Immunophenotyping
  • Leukemia, Myeloid, Acute
  • Male
  • Middle Aged
  • Prognosis
  • Proto-Oncogene Proteins c-kit
  • Tumor Markers, Biological
  • Young Adult

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