Clarithromycin in early pregnancy and the risk of miscarriage and malformation: a register based nationwide cohort study

Jon Trærup Andersen, Morten Petersen, Espen Jimenez-Solem, Kasper Brødbæk, Nadia Lyhne Andersen, Christian Torp-Pedersen, Niels Keiding, Henrik Enghusen Poulsen

40 Citations (Scopus)

Abstract

The antibiotic clarithromycin has been associated with fetal loss in animals and a study has found a doubling in the frequency of miscarriages among women using clarithromycin in pregnancy. The aim of the study was to investigate whether clarithromycin use in early pregnancy was associated with an increased risk for miscarriages and major malformations.
Original languageEnglish
JournalP L o S One
Volume8
Issue number1
Pages (from-to)e53327
ISSN1932-6203
DOIs
Publication statusPublished - 2013

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