Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Chronic endocrine consequences of traumatic brain injury - what is the evidence?

Research output: Contribution to journalReviewResearchpeer-review

DOI

  1. From conception to infancy - early risk factors for childhood obesity

    Research output: Contribution to journalReviewResearchpeer-review

  2. Glucagon-like peptide 1 in health and disease

    Research output: Contribution to journalReviewResearchpeer-review

  3. Diagnosis and management of Silver-Russell syndrome: first international consensus statement

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Therapy: Liraglutide - preventing or postponing T2DM diagnosis?

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Hippocampal volume, cognitive functions, depression, anxiety, and quality of life in patients with Cushing's syndrome

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Age-related renal function decline in Fabry disease patients on enzyme replacement therapy: a longitudinal cohort study

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Safety of switching to Migalastat from enzyme replacement therapy in Fabry disease: Experience from the Phase 3 ATTRACT study

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Cerebral infarction after fractionated stereotactic radiation therapy of benign anterior skull base tumors

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Completeness of RET testing in patients with medullary thyroid carcinoma in Denmark 1997-2013: a nationwide study

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

Traumatic brain injury (TBI) is a major public health problem with potentially debilitating consequences for the individual. Hypopituitarism after TBI has received increasing attention over the past decade; development of the condition as a consequence of TBI was previously hardly mentioned in textbooks on the subject. Hypopituitarism has been reported in more than 25% of patients with TBI and is now thought to be one of the most important causes of treatable morbidity in TBI survivors. However, most clinicians dealing with neuroendocrine diseases and TBI generally do not see such a high incidence of hypopituitarism. This disproportion is not clearly explained, but recent data indicate that diagnostic testing, which is designed for high-risk populations and not for a cohort of patients with, for example, de novo isolated growth hormone deficiency (the predominant finding in TBI), might have overestimated the true risk and disease burden of hypopituitarism. In this Opinion article, we discuss current recommendations for post-traumatic hypopituitarism in light of recent evidence.

Original languageEnglish
JournalNature reviews. Endocrinology
Volume14
Issue number1
Pages (from-to)57-62
ISSN1759-5029
DOIs
Publication statusPublished - Jan 2018

    Research areas

  • Animals, Brain Injuries, Traumatic, Humans, Hypopituitarism, Neuroendocrine Cells, Journal Article, Review

ID: 52398796