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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Choice of Treatment for Aortic Valve Stenosis in the Era of Transcatheter Aortic Valve Replacement in Eastern Denmark (2005 to 2015)

Research output: Contribution to journalJournal articlepeer-review

  1. Neo-Commissural Alignment During Transcatheter Aortic Valve Replacement: The LACRCO Algorithm

    Research output: Contribution to journalJournal articlepeer-review

  2. Does Subclinical Leaflet Thrombosis Impact the Durability of Bioprosthetic Aortic Valves?

    Research output: Contribution to journalEditorialpeer-review

  1. Three decades of heart transplantation: experience and long-term outcome

    Research output: Contribution to journalJournal articlepeer-review

  2. Transcatheter aortic valve-in-valve implantation to treat aortic Para-valvular regurgitation after TAVI

    Research output: Contribution to journalJournal articlepeer-review

  3. Neo-Commissural Alignment During Transcatheter Aortic Valve Replacement: The LACRCO Algorithm

    Research output: Contribution to journalJournal articlepeer-review

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OBJECTIVES: The aim of this study was to evaluate the choice of treatment for severe aortic valve stenosis in the era of transcatheter aortic valve replacement (TAVR) in Eastern Denmark.

BACKGROUND: Until the early 21st century, the only therapeutic option for aortic valve stenosis was surgical aortic valve replacement (SAVR), but this has changed with the introduction of TAVR.

METHODS: Using the East Denmark Heart Registry, the evolution of AVR over time was studied for the period 2005 to 2015.

RESULTS: TAVR has since its introduction in 2007 seen steady growth, with currently more than 35% of AVR procedures-and 45% of isolated AVR procedures-being performed by transcatheter-based technology. The number of SAVR procedures remained rather stable over the study period and even saw a slight decline since 2012-there was a marked decrease in the age at which surgical bioprostheses are considered appropriate. The age profile of TAVR patients remained unchanged over the study period, with a recent trend toward more low- and intermediate-risk patients. Currently, patients age ≥80 years and/or with a Society of Thoracic Surgeons (STS) surgical risk score >6 are automatically referred for TAVR, and one-half of patients age 70 to 80 years with an STS risk score of 4 to 6 are treated with TAVR.

CONCLUSIONS: The number of TAVR procedures has increased steadily in recent years, with a TAVR penetration rate of 35% in 2015 and close to 45% when considering isolated AVR. The number of SAVR procedures remained stable over the study period, and surgical bioprostheses are currently used at a much younger age than in 2005.

Original languageEnglish
JournalJACC: Cardiovascular Interventions
Volume9
Issue number11
Pages (from-to)1152-8
Number of pages7
ISSN1936-8798
DOIs
Publication statusPublished - 13 Jun 2016

    Research areas

  • Journal Article

ID: 49805222