Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
Published

Children with dyskinetic cerebral palsy are severely affected as compared to bilateral spastic cerebral palsy

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. Is earlier better when it comes giving caffeine to preterm infants or are we risking unnecessary treatment and serious harm?

    Research output: Contribution to journalEditorialResearchpeer-review

  2. Undocumented migrant children in Denmark present with diverse health needs and sometimes have critical health conditions

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Parental views on the principles for cluster randomised trials involving neonates and infants

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Structural brain maturation differs between preterm and term piglets, whereas brain activity does not

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Blødning i tredje trimester og placentakomplikationer

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

  2. Spontan chorion-amnion-separation efter vild leg

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Continuous focus on preventive strategies and follow-up is important for a change

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Everolimus as adjunctive treatment in tuberous sclerosis complex-associated epilepsy in children

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

AIM: We aimed at describing clinical findings in children with dyskinetic as compared to bilateral spastic cerebral palsy (CP).

METHODS: Data were extracted from the Danish nationwide CP register. Participants were born in 1999-2007 and were 5-6 years at ascertainment.

RESULTS: The total number of CP cases was 1165 of which 92 had dyskinetic and 540 bilateral spastic CP. Prevalence of dyskinetic CP was 0.16 per 1000 live births. In participants with dyskinetic compared to bilateral spastic CP, there was more frequently an Apgar level less than five at five minutes (22.7% vs. 11.2%) and neonatal seizures (43.5% vs. 28.5%), but less respiratory deficiency, hyperbilirubinaemia and sepsis. Impairment based on gross motor function classification was more severe in dyskinetic CP (level III-V 90.0% vs. 66.0%). In dyskinetic CP, there was a high rate of reduced developmental quotient (68.1%), visual impairment (39.3%) and epilepsy (51.6%). Basal ganglia lesions were more prevalent in dyskinetic compared to bilateral spastic CP (27.7% vs. 12.8%).

CONCLUSION: Cases of dyskinetic CP had overlapping clinical features with cases of bilateral spastic CP, but differed significantly in several perinatal risk factors. The children with dyskinetic CP had experienced more peri- or neonatal adverse events, and neurodevelopmental impairment was severe.

Original languageEnglish
JournalActa paediatrica
Volume108
Issue number10
Pages (from-to)1850-1856
ISSN1651-2227
DOIs
Publication statusPublished - Oct 2019

ID: 57239349