TY - JOUR
T1 - Characterizing incidental mass lesions in abdominal dual-energy CT compared to conventional contrast-enhanced CT
AU - Xu, Jack Junchi
AU - Ulriksen, Peter Sommer
AU - Bjerrum, Camilla Wium
AU - Achiam, Michael Patrick
AU - Resch, Timothy Andrew
AU - Lönn, Lars
AU - Lindskov Hansen, Kristoffer
PY - 2023/3
Y1 - 2023/3
N2 - BACKGROUND: Incidental findings are common in abdominal computed tomography (CT) and often warrant further investigations with economic implications as well as implications for patients.PURPOSE: To evaluate the potential of dual-energy CT (DECT) in the identification and/or characterization of abdominal incidental mass lesions compared to conventional contrast-enhanced CT.MATERIAL AND METHODS: This retrospective study from a major tertiary hospital included 96 patients, who underwent contrast-enhanced abdominal DECT. Incidental lesions in adrenals, kidneys, liver, and pancreas were evaluated by two board-certified abdominal radiologists. Observer 1 only had access to standard CT reconstructions, while observer 2 had access to standard CT as well as DECT reconstructions. Disagreements were resolved by consensus review and used as a reference for observers using McNemar's test.RESULTS: Observers 1 and 2 identified a total of 40 and 34 findings, respectively. Furthermore, observer 1 registered 13 lesions requiring follow-up, of which seven (two renal and five adrenal lesions) were resolved following consensus review using DECT (P = 0.008). The inter-observer agreement was near perfect (κ = 0.82).CONCLUSION: DECT has the potential to improve the immediate characterization of incidental findings when compared to conventional CT for abdominal imaging.
AB - BACKGROUND: Incidental findings are common in abdominal computed tomography (CT) and often warrant further investigations with economic implications as well as implications for patients.PURPOSE: To evaluate the potential of dual-energy CT (DECT) in the identification and/or characterization of abdominal incidental mass lesions compared to conventional contrast-enhanced CT.MATERIAL AND METHODS: This retrospective study from a major tertiary hospital included 96 patients, who underwent contrast-enhanced abdominal DECT. Incidental lesions in adrenals, kidneys, liver, and pancreas were evaluated by two board-certified abdominal radiologists. Observer 1 only had access to standard CT reconstructions, while observer 2 had access to standard CT as well as DECT reconstructions. Disagreements were resolved by consensus review and used as a reference for observers using McNemar's test.RESULTS: Observers 1 and 2 identified a total of 40 and 34 findings, respectively. Furthermore, observer 1 registered 13 lesions requiring follow-up, of which seven (two renal and five adrenal lesions) were resolved following consensus review using DECT (P = 0.008). The inter-observer agreement was near perfect (κ = 0.82).CONCLUSION: DECT has the potential to improve the immediate characterization of incidental findings when compared to conventional CT for abdominal imaging.
KW - Abdomen/diagnostic imaging
KW - Contrast Media
KW - Humans
KW - Liver
KW - Radiography, Dual-Energy Scanned Projection/methods
KW - Retrospective Studies
KW - Tomography, X-Ray Computed/methods
UR - http://www.scopus.com/inward/record.url?scp=85135446420&partnerID=8YFLogxK
U2 - 10.1177/02841851221116306
DO - 10.1177/02841851221116306
M3 - Journal article
C2 - 35918808
VL - 64
SP - 945
EP - 950
JO - Acta Radiologica
JF - Acta Radiologica
SN - 0284-1851
IS - 3
ER -