Changes in bone marrow lesions in response to weight-loss in obese knee osteoarthritis patients: a prospective cohort study

Henrik Gudbergsen; Mikael Boesen; Robin Christensen; Else Marie Bartels; Marius Henriksen; Bente Danneskiold-Samsøe; Henning Bliddal

doi:10.1186/1471-2474-14-106

Changes in bone marrow lesions in response to weight-loss in obese knee osteoarthritis patients: a prospective cohort study

Henrik Gudbergsen, Mikael Boesen, Robin Christensen, Else Marie Bartels, Marius Henriksen, Bente Danneskiold-Samsøe, Henning Bliddal

24 Citations (Scopus)

Abstract

Patients are susceptible for knee osteoarthritis (KOA) with increasing age and obesity and KOA is expected to become a major disabling disease in the future. An important feature of KOA on magnetic resonance imaging (MRI) is changes in the subchondral bone, bone marrow lesions (BMLs), which are related to the future degeneration of the knee joint as well as prevalent clinical symptoms. The aim of this study was to investigate the changes in BMLs after a 16-week weight-loss period in obese subjects with KOA and relate changes in BMLs to the effects of weight-loss on clinical symptoms.

Original language	English
Journal	B M C Musculoskeletal Disorders
Volume	14
Pages (from-to)	106
ISSN	1471-2474
DOIs	https://doi.org/10.1186/1471-2474-14-106
Publication status	Published - 2013

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10.1186/1471-2474-14-106

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abstract = "Patients are susceptible for knee osteoarthritis (KOA) with increasing age and obesity and KOA is expected to become a major disabling disease in the future. An important feature of KOA on magnetic resonance imaging (MRI) is changes in the subchondral bone, bone marrow lesions (BMLs), which are related to the future degeneration of the knee joint as well as prevalent clinical symptoms. The aim of this study was to investigate the changes in BMLs after a 16-week weight-loss period in obese subjects with KOA and relate changes in BMLs to the effects of weight-loss on clinical symptoms.",

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T2 - a prospective cohort study

AU - Gudbergsen, Henrik

AU - Boesen, Mikael

AU - Christensen, Robin

AU - Bartels, Else Marie

AU - Henriksen, Marius

AU - Danneskiold-Samsøe, Bente

AU - Bliddal, Henning

PY - 2013

Y1 - 2013

N2 - Patients are susceptible for knee osteoarthritis (KOA) with increasing age and obesity and KOA is expected to become a major disabling disease in the future. An important feature of KOA on magnetic resonance imaging (MRI) is changes in the subchondral bone, bone marrow lesions (BMLs), which are related to the future degeneration of the knee joint as well as prevalent clinical symptoms. The aim of this study was to investigate the changes in BMLs after a 16-week weight-loss period in obese subjects with KOA and relate changes in BMLs to the effects of weight-loss on clinical symptoms.

AB - Patients are susceptible for knee osteoarthritis (KOA) with increasing age and obesity and KOA is expected to become a major disabling disease in the future. An important feature of KOA on magnetic resonance imaging (MRI) is changes in the subchondral bone, bone marrow lesions (BMLs), which are related to the future degeneration of the knee joint as well as prevalent clinical symptoms. The aim of this study was to investigate the changes in BMLs after a 16-week weight-loss period in obese subjects with KOA and relate changes in BMLs to the effects of weight-loss on clinical symptoms.

UR - https://www.scopus.com/pages/publications/84875170052

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VL - 14

SP - 106

JO - B M C Musculoskeletal Disorders

JF - B M C Musculoskeletal Disorders

ER -

Changes in bone marrow lesions in response to weight-loss in obese knee osteoarthritis patients: a prospective cohort study

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