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Change in body mass index from childhood onwards and risk of adult cardiovascular disease

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Childhood obesity adversely affects the structure and function of the cardiovascular system, but the relationship between excessive weight gain during childhood and adult cardiovascular disease (CVD) is not fully understood. This review summarizes evidence for associations of change in body mass index (BMI) from childhood onwards with CVD outcomes. We found that excessive gain in BMI from childhood onwards was consistently associated with the presence of CVD risk factors, with increased risks of coronary heart disease, and there were suggestions of associations with stroke, atrial fibrillation and heart failure, but a lack of evidence precludes firm conclusions. These results indicate that the risk of CVD can be traced back to child ages and highlights the importance of primordial prevention of CVD by preventing excessive weight gain in childhood.

Original languageEnglish
JournalTrends in Cardiovascular Medicine
Volume30
Issue number1
Pages (from-to)39-45
Number of pages7
ISSN1050-1738
DOIs
Publication statusPublished - Jan 2020

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