Challenges of loss to follow-up in tuberculosis research

Thomas N. Nissen; Michala V Rose; Godfather Kimaro; Ib C Bygbjerg; Sayoki G Mfinanga; Pernille Ravn

doi:10.1371/journal.pone.0040183

Challenges of loss to follow-up in tuberculosis research

Thomas N. Nissen^*, Michala V Rose, Godfather Kimaro, Ib C Bygbjerg, Sayoki G Mfinanga, Pernille Ravn

^*Corresponding author for this work

12 Citations (Scopus)

Abstract

In studies evaluating methods for diagnosing tuberculosis (TB), follow-up to verify the presence or absence of active TB is crucial and high dropout rates may significantly affect the validity of the results. In a study assessing the diagnostic performance of the QuantiFERON®-TB Gold In-Tube test in TB suspect children in Tanzania, factors influencing patient adherence to attend follow-up examinations and reasons for not attending were examined.

Original language	English
Journal	P L o S One
Volume	7
Issue number	7
Pages (from-to)	e40183
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0040183
Publication status	Published - 2012

Keywords

Biomedical Research
Caregivers
Child
Child, Preschool
Communication
Female
Follow-Up Studies
Health
Humans
Infant
Lost to Follow-Up
Male
Tanzania
Tuberculosis

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10.1371/journal.pone.0040183

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title = "Challenges of loss to follow-up in tuberculosis research",

abstract = "In studies evaluating methods for diagnosing tuberculosis (TB), follow-up to verify the presence or absence of active TB is crucial and high dropout rates may significantly affect the validity of the results. In a study assessing the diagnostic performance of the QuantiFERON{\textregistered}-TB Gold In-Tube test in TB suspect children in Tanzania, factors influencing patient adherence to attend follow-up examinations and reasons for not attending were examined.",

keywords = "Biomedical Research, Caregivers, Child, Child, Preschool, Communication, Female, Follow-Up Studies, Health, Humans, Infant, Lost to Follow-Up, Male, Tanzania, Tuberculosis",

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AU - Nissen, Thomas N.

AU - Rose, Michala V

AU - Kimaro, Godfather

AU - Bygbjerg, Ib C

AU - Mfinanga, Sayoki G

AU - Ravn, Pernille

PY - 2012

Y1 - 2012

N2 - In studies evaluating methods for diagnosing tuberculosis (TB), follow-up to verify the presence or absence of active TB is crucial and high dropout rates may significantly affect the validity of the results. In a study assessing the diagnostic performance of the QuantiFERON®-TB Gold In-Tube test in TB suspect children in Tanzania, factors influencing patient adherence to attend follow-up examinations and reasons for not attending were examined.

AB - In studies evaluating methods for diagnosing tuberculosis (TB), follow-up to verify the presence or absence of active TB is crucial and high dropout rates may significantly affect the validity of the results. In a study assessing the diagnostic performance of the QuantiFERON®-TB Gold In-Tube test in TB suspect children in Tanzania, factors influencing patient adherence to attend follow-up examinations and reasons for not attending were examined.

KW - Biomedical Research

KW - Caregivers

KW - Child

KW - Child, Preschool

KW - Communication

KW - Female

KW - Follow-Up Studies

KW - Health

KW - Humans

KW - Infant

KW - Lost to Follow-Up

KW - Male

KW - Tanzania

KW - Tuberculosis

UR - https://www.scopus.com/pages/publications/84863736296

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DO - 10.1371/journal.pone.0040183

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VL - 7

SP - e40183

JO - P L o S One

JF - P L o S One

IS - 7

ER -

Challenges of loss to follow-up in tuberculosis research

Abstract

Keywords

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