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Cerebrospinal Fluid Biomarkers in Diagnosing Alzheimer's Disease in Clinical Practice: An Illustration with 3 Case Reports

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  1. Effects of long-term treatment with T-PEMF on forearm muscle activation and motor function in Parkinson's disease.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Paraneoplastic Choreoathetosis in a Patient with Small Cell Lung Carcinoma and Anti-CRMP5/CV2: A Case Report

    Research output: Contribution to journalJournal articleCommunication

  3. Familial hemiplegic migraine type 1 associated with parkinsonism: a case report

    Research output: Contribution to journalJournal articleResearch

  4. Vertebral artery dissection associated with generalized convulsive seizures: a case report

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Case report: cognitive performance in an extreme case of anorexia nervosa with a body mass index of 7.7

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Slime-loving bacteria from fresh faeces may be able to help anorexia patients

    Research output: Contribution to journalJournal articleCommunication

  3. Hvorfor fravælger halvdelen behandling for en spiseforstyrrelse?

    Research output: Contribution to journalContribution to newspaper - Newspaper articleCommunication

  4. On motivation as a Target for Intervention in Anorexia Nervosa

    Research output: Contribution to journalJournal articleResearchpeer-review

  • Diane Slats
  • Petra E Spies
  • Magnus J C Sjögren
  • Frans R J Verhey
  • Marcel M Verbeek
  • Marcel G M Olde Rikkert
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Analysis of the brain specific biomarkers amyloid beta(42) (Abeta(42)) and total tau (t-tau) protein in cerebrospinal fluid (CSF) has a sensitivity and specificity of more than 85% for differentiating Alzheimer's Disease (AD) from non-demented controls. International guidelines are contradictory in their advice on the use of CSF biomarkers in AD diagnostics, resulting in a lack of consistency in clinical practice. We present three case reports that illustrate clinical practice according to the Dutch and European guidelines and portray the value of CSF biomarker analysis as an add-on diagnostic to the standard diagnostic workup for AD.

Original languageEnglish
Book seriesCase Reports in Neurology
Volume2
Issue number1
Pages (from-to)5-11
Number of pages7
ISSN1662-680X
DOIs
Publication statusPublished - 24 Feb 2010
Externally publishedYes

ID: 49245393