Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways

A Cousins; O Olivares; E Markert; A Manoharan; X Bubnova; S Bresolin; M Degn; Z Li; D Silvestri; G McGregor; S Tumanov; D Sumpton; J J Kamphorst; A M Michie; P Herzyk; M G Valsecchi; A E Yeoh; K Schmiegelow; G Te Kronnie; E Gottlieb; C Halsey

doi:10.1038/s41375-022-01722-x

Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways

A Cousins, O Olivares, E Markert, A Manoharan, X Bubnova, S Bresolin, M Degn, Z Li, D Silvestri, G McGregor, S Tumanov, D Sumpton, J J Kamphorst, A M Michie, P Herzyk, M G Valsecchi, A E Yeoh, K Schmiegelow, G Te Kronnie, E GottliebC Halsey^*

^*Corresponding author for this work

Department of Paediatrics and Adolescent Medicine

Original language	English
Journal	Leukemia
Volume	36
Issue number	12
Pages (from-to)	2903-2907
Number of pages	5
ISSN	0887-6924
DOIs	https://doi.org/10.1038/s41375-022-01722-x
Publication status	Published - Dec 2022

Keywords

Biosynthetic Pathways
Central Nervous System
Central Nervous System Neoplasms
Cholesterol
Humans
Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics
Up-Regulation

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Cousins, A., Olivares, O., Markert, E., Manoharan, A., Bubnova, X., Bresolin, S., Degn, M., Li, Z., Silvestri, D., McGregor, G., Tumanov, S., Sumpton, D., Kamphorst, J. J., Michie, A. M., Herzyk, P., Valsecchi, M. G., Yeoh, A. E., Schmiegelow, K., Te Kronnie, G., ... Halsey, C. (2022). Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways. Leukemia, 36(12), 2903-2907. https://doi.org/10.1038/s41375-022-01722-x

Cousins, A, Olivares, O, Markert, E, Manoharan, A, Bubnova, X, Bresolin, S, Degn, M, Li, Z, Silvestri, D, McGregor, G, Tumanov, S, Sumpton, D, Kamphorst, JJ, Michie, AM, Herzyk, P, Valsecchi, MG, Yeoh, AE, Schmiegelow, K, Te Kronnie, G, Gottlieb, E & Halsey, C 2022, 'Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways', Leukemia, vol. 36, no. 12, pp. 2903-2907. https://doi.org/10.1038/s41375-022-01722-x

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title = "Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways",

keywords = "Biosynthetic Pathways, Central Nervous System, Central Nervous System Neoplasms, Cholesterol, Humans, Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics, Up-Regulation",

author = "A Cousins and O Olivares and E Markert and A Manoharan and X Bubnova and S Bresolin and M Degn and Z Li and D Silvestri and G McGregor and S Tumanov and D Sumpton and Kamphorst, {J J} and Michie, {A M} and P Herzyk and Valsecchi, {M G} and Yeoh, {A E} and K Schmiegelow and {Te Kronnie}, G and E Gottlieb and C Halsey",

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doi = "10.1038/s41375-022-01722-x",

language = "English",

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T1 - Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways

AU - Cousins, A

AU - Olivares, O

AU - Markert, E

AU - Manoharan, A

AU - Bubnova, X

AU - Bresolin, S

AU - Degn, M

AU - Li, Z

AU - Silvestri, D

AU - McGregor, G

AU - Tumanov, S

AU - Sumpton, D

AU - Kamphorst, J J

AU - Michie, A M

AU - Herzyk, P

AU - Valsecchi, M G

AU - Yeoh, A E

AU - Schmiegelow, K

AU - Te Kronnie, G

AU - Gottlieb, E

AU - Halsey, C

PY - 2022/12

Y1 - 2022/12

KW - Biosynthetic Pathways

KW - Central Nervous System

KW - Central Nervous System Neoplasms

KW - Cholesterol

KW - Humans

KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics

KW - Up-Regulation

UR - http://www.scopus.com/inward/record.url?scp=85140626822&partnerID=8YFLogxK

U2 - 10.1038/s41375-022-01722-x

DO - 10.1038/s41375-022-01722-x

M3 - Letter

C2 - 36289348

SN - 0887-6924

VL - 36

SP - 2903

EP - 2907

JO - Leukemia

JF - Leukemia

IS - 12

ER -

Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways

Keywords

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