TY - JOUR
T1 - Ceftriaxone-resistant Salmonella enterica serotype Typhi in a pregnant traveller returning from Karachi, Pakistan to Denmark, 2019
AU - Engsbro, Anne Line
AU - Riis Jespersen, Hans Søe
AU - Goldschmidt, Maria Ingeborg
AU - Mollerup, Sarah
AU - Worning, Peder
AU - Pedersen, Martin Schou
AU - Westh, Henrik
AU - Schneider, Uffe Vest
PY - 2019/5/23
Y1 - 2019/5/23
N2 - We describe a ceftriaxone-resistant Salmonella Typhi bacteraemia in a pregnant woman returning from a family visit in Pakistan. Whole genome sequencing confirmed similarity to a Pakistani outbreak clone. Pregnancy and unawareness of this outbreak delayed appropriate antibiotic therapy. Concurrently, we detected faecal carriage of a carbapenemase-producing Escherichia coli. Awareness of the ongoing outbreak should affect empiric treatment of typhoid fever and hygiene precautions in travellers returning from Pakistan. Meropenem may be warranted in severe cases.
AB - We describe a ceftriaxone-resistant Salmonella Typhi bacteraemia in a pregnant woman returning from a family visit in Pakistan. Whole genome sequencing confirmed similarity to a Pakistani outbreak clone. Pregnancy and unawareness of this outbreak delayed appropriate antibiotic therapy. Concurrently, we detected faecal carriage of a carbapenemase-producing Escherichia coli. Awareness of the ongoing outbreak should affect empiric treatment of typhoid fever and hygiene precautions in travellers returning from Pakistan. Meropenem may be warranted in severe cases.
UR - http://www.scopus.com/inward/record.url?scp=85067304994&partnerID=8YFLogxK
U2 - 10.2807/1560-7917.ES.2019.24.21.1900289
DO - 10.2807/1560-7917.ES.2019.24.21.1900289
M3 - Journal article
C2 - 31138366
VL - 24
JO - Eurosurveillance
JF - Eurosurveillance
SN - 1560-7917
IS - 21
ER -