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Causes of hospital admissions in Domus: a randomized controlled trial of specialized palliative cancer care at home

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@article{689cade9c6234b16933e1c080847e082,
title = "Causes of hospital admissions in Domus: a randomized controlled trial of specialized palliative cancer care at home",
abstract = "PURPOSE: Avoidable hospital admissions are important negative indicators of quality of end-of-life care. Specialized palliative care (SPC) may support patients in remaining at home. Therefore, the purpose of this study was to investigate if SPC at home could prevent hospital admissions in patients with incurable cancer.PATIENTS AND METHODS: These are secondary results of Domus: a randomized controlled trial of accelerated transition to SPC with psychological intervention at home (clinicaltrials.gov: NCT01885637). Participants were patients with incurable cancer and limited antineoplastic treatment options and their caregivers. They were included from the Department of Oncology, Rigshospitalet, Denmark between 2013 and 2016. The control group received usual care. Outcomes were hospital admissions, causes thereof, and patient and caregiver perceptions of place of care (home, hospital etc.) at baseline, 4 weeks, 8 weeks, and 6 months.RESULTS: During the study, 340 patients were randomized and 322 were included in modified intention-to-treat analyses. Overall, there were no significant differences in hospital admissions between the groups. The intervention group had more admissions triggered by worsened general health (22% v 16%, p=0.0436) or unmanageable home situation (8% v 4%, p=0.0119). After diagnostics, admissions were more often caused by clinical symptoms of cancer without progression in the intervention group (11% v 7%, p=0.0493). The two groups did not differ significantly in overall potentially avoidable admissions. Both groups felt mostly safe about their place of care.CONCLUSION: The intervention did not prevent hospital admissions. Likely, any intervention effects were outweighed by increased identification of problems in the intervention group leading to hospital admissions. Overall, patients and caregivers felt safe in their current place of care.",
keywords = "Journal Article",
author = "Benthien, {Kirstine Skov} and Mie Nordly and {von Heymann-Horann}, Annika and Kristina Holmenlund and Helle Timm and Geana Kurita and Christoffer Johansen and Jakob Kjellberg and {von der Maase}, Hans and Per Sj{\o}gren",
note = "Copyright {\textcopyright} 2017. Published by Elsevier Inc.",
year = "2018",
doi = "10.1016/j.jpainsymman.2017.10.007",
language = "English",
volume = "55",
pages = "728--736",
journal = "Journal of Pain and Symptom Management",
issn = "0885-3924",
publisher = "Elsevier Inc",
number = "3",

}

RIS

TY - JOUR

T1 - Causes of hospital admissions in Domus

T2 - a randomized controlled trial of specialized palliative cancer care at home

AU - Benthien, Kirstine Skov

AU - Nordly, Mie

AU - von Heymann-Horann, Annika

AU - Holmenlund, Kristina

AU - Timm, Helle

AU - Kurita, Geana

AU - Johansen, Christoffer

AU - Kjellberg, Jakob

AU - von der Maase, Hans

AU - Sjøgren, Per

N1 - Copyright © 2017. Published by Elsevier Inc.

PY - 2018

Y1 - 2018

N2 - PURPOSE: Avoidable hospital admissions are important negative indicators of quality of end-of-life care. Specialized palliative care (SPC) may support patients in remaining at home. Therefore, the purpose of this study was to investigate if SPC at home could prevent hospital admissions in patients with incurable cancer.PATIENTS AND METHODS: These are secondary results of Domus: a randomized controlled trial of accelerated transition to SPC with psychological intervention at home (clinicaltrials.gov: NCT01885637). Participants were patients with incurable cancer and limited antineoplastic treatment options and their caregivers. They were included from the Department of Oncology, Rigshospitalet, Denmark between 2013 and 2016. The control group received usual care. Outcomes were hospital admissions, causes thereof, and patient and caregiver perceptions of place of care (home, hospital etc.) at baseline, 4 weeks, 8 weeks, and 6 months.RESULTS: During the study, 340 patients were randomized and 322 were included in modified intention-to-treat analyses. Overall, there were no significant differences in hospital admissions between the groups. The intervention group had more admissions triggered by worsened general health (22% v 16%, p=0.0436) or unmanageable home situation (8% v 4%, p=0.0119). After diagnostics, admissions were more often caused by clinical symptoms of cancer without progression in the intervention group (11% v 7%, p=0.0493). The two groups did not differ significantly in overall potentially avoidable admissions. Both groups felt mostly safe about their place of care.CONCLUSION: The intervention did not prevent hospital admissions. Likely, any intervention effects were outweighed by increased identification of problems in the intervention group leading to hospital admissions. Overall, patients and caregivers felt safe in their current place of care.

AB - PURPOSE: Avoidable hospital admissions are important negative indicators of quality of end-of-life care. Specialized palliative care (SPC) may support patients in remaining at home. Therefore, the purpose of this study was to investigate if SPC at home could prevent hospital admissions in patients with incurable cancer.PATIENTS AND METHODS: These are secondary results of Domus: a randomized controlled trial of accelerated transition to SPC with psychological intervention at home (clinicaltrials.gov: NCT01885637). Participants were patients with incurable cancer and limited antineoplastic treatment options and their caregivers. They were included from the Department of Oncology, Rigshospitalet, Denmark between 2013 and 2016. The control group received usual care. Outcomes were hospital admissions, causes thereof, and patient and caregiver perceptions of place of care (home, hospital etc.) at baseline, 4 weeks, 8 weeks, and 6 months.RESULTS: During the study, 340 patients were randomized and 322 were included in modified intention-to-treat analyses. Overall, there were no significant differences in hospital admissions between the groups. The intervention group had more admissions triggered by worsened general health (22% v 16%, p=0.0436) or unmanageable home situation (8% v 4%, p=0.0119). After diagnostics, admissions were more often caused by clinical symptoms of cancer without progression in the intervention group (11% v 7%, p=0.0493). The two groups did not differ significantly in overall potentially avoidable admissions. Both groups felt mostly safe about their place of care.CONCLUSION: The intervention did not prevent hospital admissions. Likely, any intervention effects were outweighed by increased identification of problems in the intervention group leading to hospital admissions. Overall, patients and caregivers felt safe in their current place of care.

KW - Journal Article

U2 - 10.1016/j.jpainsymman.2017.10.007

DO - 10.1016/j.jpainsymman.2017.10.007

M3 - Journal article

C2 - 29056562

VL - 55

SP - 728

EP - 736

JO - Journal of Pain and Symptom Management

JF - Journal of Pain and Symptom Management

SN - 0885-3924

IS - 3

ER -

ID: 52146243