Case fatality ratio and mortality rate trends of community-onset Staphylococcus aureus bacteraemia

S Tom, J C Galbraith, L Valiquette, G Jacobsson, P Collignon, H C Schønheyder, M Søgaard, K J Kennedy, Inge Jenny Dahl Knudsen, Christian Østergaard Andersen, O Lyytikäinen, K B Laupland, International Bacteraemia Surveillance Collaborative

33 Citations (Scopus)

Abstract

Lethal outcomes can be expressed as a case fatality ratio (CFR) or as a mortality rate per 100 000 population per year (MR). Population surveillance for community-onset methicillin-sensitive (MSSA) and methicillin-resistant (MRSA) Staphylococcus aureus bacteraemia was conducted in Canada, Australia, Sweden and Denmark to evaluate 30-day CFR and MR trends between 2000 and 2008. The CFR was 20.3% (MSSA 20.2%, MRSA 22.3%) and MR was 3.4 (MSSA 3.1, MRSA 0.3) per 100 000 per year. Although MSSA CFR was stable the MSSA MR increased; MRSA CFR decreased while its MR remained low during the study. Community-onset S. aureus bacteraemia, particularly MSSA, is associated with major disease burden. This study highlights complementary information provided by evaluating both CFR and MR.

Original languageEnglish
JournalClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
Volume20
Issue number10
Pages (from-to)O630-2
ISSN1198-743X
DOIs
Publication statusPublished - 2014

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