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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Cardiovascular Risk is not Increased in Patients with Chronic Urticaria: A Retrospective Population-based Cohort Study

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  1. A Challenging Case of Subcutaneous and Mucosal Haemorrhage Caused by Urticarial Vasculitis (Urticaria Haemorrhagica Profunda)

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  2. Long-lasting Tumour on the Upper Lip of a 28-year-old Woman: A Quiz

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  3. Patient-reported Outcomes During Treatment in Patients with Moderate-to-severe Psoriasis: A Danish Nationwide Study

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  1. Incidence of Ischemic Stroke in Individuals With and Without Aortic Valve Stenosis: A Danish Retrospective Cohort Study

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  2. Cardiovascular complications in patients with total cavopulmonary connection: A nationwide cohort study

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  3. Favorable five-year outcomes for heart failure diagnosed in younger patients without severe comorbidity

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  4. Quality of life and the associated risk of all-cause mortality in nonischemic heart failure

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  5. Does type 2 diabetes confer higher relative rates of cardiovascular events in women compared with men?

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Chronic urticaria (CU) is a common condition characterized by daily or almost daily occurrence of wheals, angioedema, or both over a period of more than 6 weeks (1). CU is classified into inducible (CIndU) and spontaneous forms (CSU). The annual period prevalence of CSU was recently estimated in an Italian cohort as between 0.02% and 0.38%, whereas a German study showed a lifetime prevalence of CU at 1.8% (2, 3). While an association between CU and certain autoimmune diseases is well-established (3), CSU was surprisingly associated with obesity in a recent Italian study (4). Moreover, in a South Korean cohort of 131 patients with CU, metabolic syndrome was present in 30% of patients, and these individuals had particularly poor clinical outcomes and a more severe disease course (5). Finally, a population-based Taiwanese study of 9798 adults with CU recently showed that the condition was significantly associated with having received a prior diagnosis of hyperlipidaemia (6). Despite the above observations, no study has examined a possible association between CU and cardiovascular (CV) disease. We therefore investigated the risk of myocardial infarction (MI), ischaemic stroke, CV death, and major adverse CV events (MACE; a composite of MI, ischemic stroke, and CV death), in patients with CU and CIndU, respectively, in a nationwide cohort using prospectively collected administrative data. © 2017 Acta Dermato-Venereologica.
Original languageEnglish
JournalActa Dermatovenereologica
Volume97
Issue number2
Pages (from-to)261-262
ISSN0001-5555
DOIs
Publication statusPublished - Feb 2017

ID: 48898620