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Cardiovascular health effects following exposure of human volunteers during fire extinction exercises

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Andersen, MHG, Saber, AT, Pedersen, PB, Loft, S, Hansen, ÅM, Koponen, IK, Pedersen, JE, Ebbehøj, N, Nørskov, E-C, Clausen, PA, Garde, AH, Vogel, U & Møller, P 2017, 'Cardiovascular health effects following exposure of human volunteers during fire extinction exercises' Environmental Health: A Global Access Science Source, vol. 16, no. 1, pp. 96. https://doi.org/10.1186/s12940-017-0303-8

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Author

Andersen, Maria Helena Guerra ; Saber, Anne Thoustrup ; Pedersen, Peter Bøgh ; Loft, Steffen ; Hansen, Åse Marie ; Koponen, Ismo Kalevi ; Pedersen, Julie Elbæk ; Ebbehøj, Niels ; Nørskov, Eva-Carina ; Clausen, Per Axel ; Garde, Anne Helene ; Vogel, Ulla ; Møller, Peter. / Cardiovascular health effects following exposure of human volunteers during fire extinction exercises. In: Environmental Health: A Global Access Science Source. 2017 ; Vol. 16, No. 1. pp. 96.

Bibtex

@article{2e6a22e018e2488986627ef744b56b87,
title = "Cardiovascular health effects following exposure of human volunteers during fire extinction exercises",
abstract = "BACKGROUND: Firefighters have increased risk of cardiovascular disease and of sudden death from coronary heart disease on duty while suppressing fires. This study investigated the effect of firefighting activities, using appropriate personal protective equipment (PPE), on biomarkers of cardiovascular effects in young conscripts training to become firefighters.METHODS: Healthy conscripts (n = 43) who participated in a rescue educational course for firefighting were enrolled in the study. The exposure period consisted of a three-day training course where the conscripts participated in various firefighting exercises in a constructed firehouse and flashover container. The subjects were instructed to extinguish fires of either wood or wood with electrical cords and mattresses. The exposure to particulate matter (PM) was assessed at various locations and personal exposure was assessed by portable PM samplers and urinary excretion of 1-hydroxypyrene. Cardiovascular measurements included microvascular function and heart rate variability (HRV).RESULTS: The subjects were primarily exposed to PM in bystander positions, whereas self-contained breathing apparatus effectively abolished pulmonary exposure. Firefighting training was associated with elevated urinary excretion of 1-hydroxypyrene (105{\%}, 95{\%} CI: 52; 157{\%}), increased body temperature, decreased microvascular function (-18{\%}, 95{\%} CI: -26; -9{\%}) and altered HRV. There was no difference in cardiovascular measurements for the two types of fires.CONCLUSION: Observations from this fire extinction training show that PM exposure mainly occurs in situations where firefighters removed the self-contained breathing apparatus. Altered cardiovascular disease endpoints after the firefighting exercise period were most likely due to complex effects from PM exposure, physical exhaustion and increased core body temperature.",
keywords = "Air Pollutants/adverse effects, Air Pollution, Indoor/adverse effects, Biomarkers/urine, Cardiovascular Physiological Phenomena, Firefighters/statistics & numerical data, Fires/statistics & numerical data, Healthy Volunteers, Heart Rate, Humans, Motor Activity, Occupational Exposure, Particulate Matter/adverse effects, Personal Protective Equipment/statistics & numerical data, Pyrenes/urine",
author = "Andersen, {Maria Helena Guerra} and Saber, {Anne Thoustrup} and Pedersen, {Peter B{\o}gh} and Steffen Loft and Hansen, {{\AA}se Marie} and Koponen, {Ismo Kalevi} and Pedersen, {Julie Elb{\ae}k} and Niels Ebbeh{\o}j and Eva-Carina N{\o}rskov and Clausen, {Per Axel} and Garde, {Anne Helene} and Ulla Vogel and Peter M{\o}ller",
year = "2017",
month = "9",
day = "6",
doi = "10.1186/s12940-017-0303-8",
language = "English",
volume = "16",
pages = "96",
journal = "Environmental Health: A Global Access Science Source",
issn = "1476-069X",
publisher = "BioMed Central Ltd",
number = "1",

}

RIS

TY - JOUR

T1 - Cardiovascular health effects following exposure of human volunteers during fire extinction exercises

AU - Andersen, Maria Helena Guerra

AU - Saber, Anne Thoustrup

AU - Pedersen, Peter Bøgh

AU - Loft, Steffen

AU - Hansen, Åse Marie

AU - Koponen, Ismo Kalevi

AU - Pedersen, Julie Elbæk

AU - Ebbehøj, Niels

AU - Nørskov, Eva-Carina

AU - Clausen, Per Axel

AU - Garde, Anne Helene

AU - Vogel, Ulla

AU - Møller, Peter

PY - 2017/9/6

Y1 - 2017/9/6

N2 - BACKGROUND: Firefighters have increased risk of cardiovascular disease and of sudden death from coronary heart disease on duty while suppressing fires. This study investigated the effect of firefighting activities, using appropriate personal protective equipment (PPE), on biomarkers of cardiovascular effects in young conscripts training to become firefighters.METHODS: Healthy conscripts (n = 43) who participated in a rescue educational course for firefighting were enrolled in the study. The exposure period consisted of a three-day training course where the conscripts participated in various firefighting exercises in a constructed firehouse and flashover container. The subjects were instructed to extinguish fires of either wood or wood with electrical cords and mattresses. The exposure to particulate matter (PM) was assessed at various locations and personal exposure was assessed by portable PM samplers and urinary excretion of 1-hydroxypyrene. Cardiovascular measurements included microvascular function and heart rate variability (HRV).RESULTS: The subjects were primarily exposed to PM in bystander positions, whereas self-contained breathing apparatus effectively abolished pulmonary exposure. Firefighting training was associated with elevated urinary excretion of 1-hydroxypyrene (105%, 95% CI: 52; 157%), increased body temperature, decreased microvascular function (-18%, 95% CI: -26; -9%) and altered HRV. There was no difference in cardiovascular measurements for the two types of fires.CONCLUSION: Observations from this fire extinction training show that PM exposure mainly occurs in situations where firefighters removed the self-contained breathing apparatus. Altered cardiovascular disease endpoints after the firefighting exercise period were most likely due to complex effects from PM exposure, physical exhaustion and increased core body temperature.

AB - BACKGROUND: Firefighters have increased risk of cardiovascular disease and of sudden death from coronary heart disease on duty while suppressing fires. This study investigated the effect of firefighting activities, using appropriate personal protective equipment (PPE), on biomarkers of cardiovascular effects in young conscripts training to become firefighters.METHODS: Healthy conscripts (n = 43) who participated in a rescue educational course for firefighting were enrolled in the study. The exposure period consisted of a three-day training course where the conscripts participated in various firefighting exercises in a constructed firehouse and flashover container. The subjects were instructed to extinguish fires of either wood or wood with electrical cords and mattresses. The exposure to particulate matter (PM) was assessed at various locations and personal exposure was assessed by portable PM samplers and urinary excretion of 1-hydroxypyrene. Cardiovascular measurements included microvascular function and heart rate variability (HRV).RESULTS: The subjects were primarily exposed to PM in bystander positions, whereas self-contained breathing apparatus effectively abolished pulmonary exposure. Firefighting training was associated with elevated urinary excretion of 1-hydroxypyrene (105%, 95% CI: 52; 157%), increased body temperature, decreased microvascular function (-18%, 95% CI: -26; -9%) and altered HRV. There was no difference in cardiovascular measurements for the two types of fires.CONCLUSION: Observations from this fire extinction training show that PM exposure mainly occurs in situations where firefighters removed the self-contained breathing apparatus. Altered cardiovascular disease endpoints after the firefighting exercise period were most likely due to complex effects from PM exposure, physical exhaustion and increased core body temperature.

KW - Air Pollutants/adverse effects

KW - Air Pollution, Indoor/adverse effects

KW - Biomarkers/urine

KW - Cardiovascular Physiological Phenomena

KW - Firefighters/statistics & numerical data

KW - Fires/statistics & numerical data

KW - Healthy Volunteers

KW - Heart Rate

KW - Humans

KW - Motor Activity

KW - Occupational Exposure

KW - Particulate Matter/adverse effects

KW - Personal Protective Equipment/statistics & numerical data

KW - Pyrenes/urine

U2 - 10.1186/s12940-017-0303-8

DO - 10.1186/s12940-017-0303-8

M3 - Journal article

VL - 16

SP - 96

JO - Environmental Health: A Global Access Science Source

JF - Environmental Health: A Global Access Science Source

SN - 1476-069X

IS - 1

ER -

ID: 57732157