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Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area

Anna K Kähler, Srdjan Djurovic, Lars M Rimol, Andrew Anand Brown, Lavinia Athanasiu, Erik G Jönsson, Thomas Hansen, Omar Gústafsson, Håkan Hall, Ina Giegling, Pierandrea Muglia, Sven Cichon, Marcella Rietschel, Olli P H Pietiläinen, Leena Peltonen, Elvira Bramon, David Collier, David St Clair, Engilbert Sigurdsson, Hannes PeturssonDan Rujescu, Ingrid Melle, Thomas Werge, Vidar M Steen, Anders M Dale, Russell T Matthews, Ingrid Agartz, Ole A Andreassen

39 Citations (Scopus)

Abstract

The Human Natural Killer-1 carbohydrate (HNK-1) is involved in neurodevelopment and synaptic plasticity. Extracellular matrix structures called perineuronal nets, condensed around subsets of neurons and proximal dendrites during brain maturation, regulate synaptic transmission and plasticity.
Original languageEnglish
JournalBiological Psychiatry
Volume69
Issue number1
Pages (from-to)90-6
Number of pages7
ISSN0006-3223
DOIs
Publication statusPublished - 1 Jan 2011

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