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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Cancer of the corpus uteri

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  1. Characteristics, management and outcomes of very preterm triplets in 19 European regions

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  2. FIGO classification for the clinical diagnosis of placenta accreta spectrum disorders

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  3. Self-perceived long-term transfer of learning after postpartum hemorrhage simulation training

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  4. FIGO consensus guidelines on placenta accreta spectrum disorders: Introduction

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  5. FIGO consensus guidelines on placenta accreta spectrum disorders: Epidemiology

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Endometrial cancer is the most common gynecological malignancy in high-income countries. Although the overall prognosis is relatively good, high-grade endometrial cancers have a tendency to recur. Recurrence needs to be prevented since the prognosis for recurrent endometrial cancer is dismal. Treatment tailored to tumor biology is the optimal strategy to balance treatment efficacy against toxicity. Standard treatment consists of hysterectomy and bilateral salpingo-oophorectomy. Lymphadenectomy (with ongoing studies of sentinel node biopsy) enables identification of lymph node positive patients who need adjuvant treatment, including radiotherapy and chemotherapy. Adjuvant radiotherapy is used for Stage I-II patients with high-risk factors and Stage III lymph node negative patients. In advanced disease, a combination of surgery to no residual disease and chemotherapy results in the best outcome. Surgery for recurrent disease is only advocated in patients with a good performance status with a relatively long disease-free interval.

Original languageEnglish
JournalInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Volume143 Suppl 2
Pages (from-to)37-50
Number of pages14
ISSN0020-7292
DOIs
Publication statusPublished - Oct 2018

    Research areas

  • Aged, Endometrial Neoplasms/pathology, Female, Humans, Hysterectomy/methods, Lymph Node Excision/methods, Middle Aged, Neoplasm Recurrence, Local/pathology, Neoplasm Staging, Prognosis, Radiotherapy, Adjuvant, Salpingo-oophorectomy/methods

ID: 55906993