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Calcitonin gene-related peptide does not cause migraine attacks in patients with familial hemiplegic migraine

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Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP triggers migraine-like attacks in patients with migraine with aura and without aura. In contrast, patients with familial hemiplegic migraine (FHM) with known mutations did not report more migraine-like attacks compared to controls. Whether CGRP triggers migraine-like attacks in FHM patients without known mutations is unknown.
Original languageEnglish
JournalHeadache
Volume51
Issue number4
Pages (from-to)544-53
Number of pages10
ISSN0017-8748
DOIs
Publication statusPublished - 2011

ID: 34669496