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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum

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  1. Epilepsy in Individuals with a History of Asperger's Syndrome: A Danish Nationwide Register-Based Cohort Study

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Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) frequently co-occur and show high genetic correlation. With the introduction of DSM-5, there is a new concept of an ASD and/or ADHD spectrum (ASD/ADHD). This study aimed to identify predictors of severity and need of healthcare within this spectrum. 39 families with multiple individuals affected by ASD/ADHD were recruited from a psychiatric clinic. Diagnoses, functional and demographic characteristics were retrieved from journals while hospital admissions were identified in the Danish health register. An estimated fraction of 31% ASD/ADHD patients had never been hospitalized and 35% remained undiagnosed despite hospitalization. Cluster analysis identified trajectories that discriminate age of diagnosis, educational attainment to degree of severity, need of hospitalization and genetic risk.

Original languageEnglish
JournalJournal of Autism and Developmental Disorders
Volume48
Issue number10
Pages (from-to)3629-3636
Number of pages8
ISSN0162-3257
DOIs
Publication statusPublished - Oct 2018

ID: 54600168