Research
Print page Print page
Switch language
The Capital Region of Denmark - a part of Copenhagen University Hospital
E-pub ahead of print

Bone mineral density is preserved in men with idiopathic infertility

Research output: Contribution to journalJournal articleResearchpeer-review

DOI

  1. An update on semen quality among young Finnish men and comparison with Danish data

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer?

    Research output: Contribution to journalJournal articleResearchpeer-review

  1. Populations, decreasing fertility, and reproductive health

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy

    Research output: Contribution to journalJournal articleResearchpeer-review

View graph of relations

BACKGROUND: Lower semen quality is associated with increased mortality and morbidity, which may include osteoporosis.

OBJECTIVE: To assess whether infertile men have a lower bone mineral density (BMD) compared with fertile men at the time of fertility workup.

METHODS: A total of 146 men from infertile couples with unexplained impaired semen quality, characterized by sperm concentration < 20 million/mL, progressive motility < 50% or < 12% morphologically normal spermatozoa. Men with infertility due to a genetic etiology or a condition that could cause testicular damage were excluded. A total of 271 men from couples with an ongoing naturally conceived pregnancy served as a control group. Lumbar, femoral, and total body BMD were measured by dual X-ray absorptiometry.

RESULTS: Infertile men had similar BMD compared with fertile men (Beta coefficient (g/cm2 ) and 95% confidence interval for the difference between the two groups: -0.02 (-0.05; 0.01) for lumbar BMD, -0.02 (-0.05; 0.01) for femoral neck BMD, -0.01 (-0.04; 0.02) for total femur BMD, and -0.01 (-0.03; 0.01) for total body BMD). Semen parameters were not associated with BMD measurements. Furthermore, BMD did not differ between infertile men with the lowest semen quality vs. infertile men with better semen quality nor between infertile men with low testosterone vs. fertile men with normal testosterone levels.

CONCLUSION: Bone mineral density is preserved in men with unexplained infertility at the time of fertility workup.

Original languageEnglish
JournalAndrology
ISSN2047-2919
DOIs
Publication statusE-pub ahead of print - 2 Aug 2019

ID: 57781304