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The Capital Region of Denmark - a part of Copenhagen University Hospital
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Body weight-supported training in Becker and limb girdle 2I muscular dystrophy

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INTRODUCTION: We studied the functional effects of combined strength and aerobic anti-gravity training in severely affected patients with Becker and Limb-Girdle muscular dystrophies.

METHODS: Eight patients performed 10-week progressive combined strength (squats, calf raises, lunges) and aerobic (walk/run, jogging in place or high knee-lift) training 3 times/week in a lower-body positive pressure environment. Closed-kinetic-chain leg muscle strength, isometric knee strength, rate of force development (RFD), and reaction time were evaluated.

RESULTS: Baseline data indicated an intact neural activation pattern but showed compromised muscle contractile properties. Training (compliance 91%) improved functional leg muscle strength. Squat series performance increased 30%, calf raises 45%, and lunges 23%.

CONCLUSIONS: Anti-gravity training improved closed-kinetic-chain leg muscle strength despite no changes in isometric knee extension strength and absolute RFD. The improved closed-kinetic-chain performance may relate to neural adaptation involving motor learning and/or improved muscle strength of other muscles than the weak knee extensors. Muscle Nerve 54: 239-243, 2016.

Original languageEnglish
JournalMuscle and Nerve
Volume54
Issue number2
Pages (from-to)239-43
Number of pages5
ISSN0148-639X
DOIs
Publication statusPublished - Aug 2016

    Research areas

  • Journal Article

ID: 49288223