Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Body fat throughout childhood in 2647 healthy Danish children
T2 - agreement of BMI, waist circumference, skinfolds with dual X-ray absorptiometry
AU - Wohlfahrt-Veje, C
AU - Tinggaard, J
AU - Winther, K
AU - Mouritsen, A
AU - Hagen, C P
AU - Mieritz, M G
AU - de Renzy-Martin, K T
AU - Boas, M
AU - Petersen, J H
AU - Main, K M
PY - 2014/6
Y1 - 2014/6
N2 - BACKGROUND/OBJECTIVES: Total body fat percentage (%BF) evaluated by dual energy X-ray absorptiometry (DXA) scans (DXA %BF) is widely recognized as a precise measure of fatness. We aimed to establish national reference curves for DXA %BF, %BF calculated from skinfolds (SF %BF) and waist circumference (WC) in healthy children, and to compare agreement between the different methods.SUBJECTS/METHODS: Based on 11 481 physical examinations (anthropometry) and 1200 DXA scans from a longitudinal cohort of Danish children (n=2647), we established reference curves (LMS-method) for SF %BF, WC (birth to 14 years) and DXA %BF (8-14 years). Age- and sex-specific Z-scores for body mass index (BMI), WC and SF %BF were compared. Sensitivity and specificity were calculated for agreement of WC, SF %BF and BMI with DXA %BF to identify obese children (>+1 s.d.).RESULTS: %BF differed with age, sex, pubertal stage and social class. SF %BF correlated strongly with DXA %BF (r=0.86). BMI and WC also correlated positively with DXA %BF (Z-scores; r= 0.78 and 0.69). Sensitivity and specificity were 79.5 and 93.8 for SF %BF, 75.9 and 90.3 for BMI and 59.2 and 95.4 for WC.CONCLUSIONS: SF %BF showed the highest correlation and best agreement with DXA %BF in identifying children with excess fat (+1 s.d.).
AB - BACKGROUND/OBJECTIVES: Total body fat percentage (%BF) evaluated by dual energy X-ray absorptiometry (DXA) scans (DXA %BF) is widely recognized as a precise measure of fatness. We aimed to establish national reference curves for DXA %BF, %BF calculated from skinfolds (SF %BF) and waist circumference (WC) in healthy children, and to compare agreement between the different methods.SUBJECTS/METHODS: Based on 11 481 physical examinations (anthropometry) and 1200 DXA scans from a longitudinal cohort of Danish children (n=2647), we established reference curves (LMS-method) for SF %BF, WC (birth to 14 years) and DXA %BF (8-14 years). Age- and sex-specific Z-scores for body mass index (BMI), WC and SF %BF were compared. Sensitivity and specificity were calculated for agreement of WC, SF %BF and BMI with DXA %BF to identify obese children (>+1 s.d.).RESULTS: %BF differed with age, sex, pubertal stage and social class. SF %BF correlated strongly with DXA %BF (r=0.86). BMI and WC also correlated positively with DXA %BF (Z-scores; r= 0.78 and 0.69). Sensitivity and specificity were 79.5 and 93.8 for SF %BF, 75.9 and 90.3 for BMI and 59.2 and 95.4 for WC.CONCLUSIONS: SF %BF showed the highest correlation and best agreement with DXA %BF in identifying children with excess fat (+1 s.d.).
KW - Absorptiometry, Photon
KW - Adipose Tissue
KW - Adolescent
KW - Age Factors
KW - Anthropometry
KW - Body Composition
KW - Body Mass Index
KW - Child
KW - Child, Preschool
KW - Denmark
KW - Humans
KW - Infant
KW - Infant, Newborn
KW - Longitudinal Studies
KW - Male
KW - Pediatric Obesity
KW - Puberty
KW - Reference Values
KW - Sensitivity and Specificity
KW - Sex Factors
KW - Skinfold Thickness
KW - Social Class
KW - Waist Circumference
U2 - 10.1038/ejcn.2013.282
DO - 10.1038/ejcn.2013.282
M3 - Journal article
VL - 68
SP - 664
EP - 670
JO - European Journal of Clinical Nutrition
JF - European Journal of Clinical Nutrition
SN - 0954-3007
IS - 6
ER -
ID: 44830374